Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury

Hiroshi Maekawa, Tsuyoshi Inoue, Haruki Ouchi, +9

Cell Reports

Mitochondrial DysfunctionImmunologyRenal InflammationCell DeathInnate Immunity +17

beta 2-Microglobulin modified with advanced glycation end products is a major component of hemodialysis-associated amyloidosis.

Toshio Miyata, Osamu Oda, Reiko Inagi, +7

Journal of Clinical Investigation

BiochemistryMajor ComponentMedicineAmyloid FibrilsBioanalysis +12

Human Herpesvirus 6 Infection as a Risk Factor for the Development of Severe Drug-Induced Hypersensitivity Syndrome

Yosuke Suzuki, Reiko Inagi, Toshiya Aono, +2

Archives of Dermatology

Involvement of beta 2-microglobulin modified with advanced glycation end products in the pathogenesis of hemodialysis-associated amyloidosis. Induction of human monocyte chemotaxis and macrophage secretion of tumor necrosis factor-alpha and interleukin-1.

Toshio Miyata, Reiko Inagi, Yuichiro Iida, +5

Journal of Clinical Investigation

ImmunologyGlycobiologyPathologyNeuroinflammationInflammation +15

Angiotensin II Receptor Antagonists and Angiotensin-Converting Enzyme Inhibitors Lower In Vitro the Formation of Advanced Glycation End Products

Toshio Miyata, Charles van Ypersele de Strihou, Yasuhiko Ueda, +6

Journal of the American Society of Nephrology

Severe Hypersensitivity Syndrome Due to Sulfasalazine Associated With Reactivation of Human Herpesvirus 6

Mikiko Tohyama, Yoko Yahata, Masaki Yasukawa, +4

Archives of Dermatology

Immunohistochemical Evidence for an Increased Oxidative Stress and Carbonyl Modification of Proteins in Diabetic Glomerular Lesions

Daisuke Suzuki, Toshio Miyata, Noboru Saotome, +8

Journal of the American Society of Nephrology

Evidence of Tubular Hypoxia in the Early Phase in the Remnant Kidney Model

Krissanapong Manotham, Tetsuhiro Tanaka, Makiko Matsumoto, +6

Journal of the American Society of Nephrology

Imbalance of T-Cell Subsets in Angiotensin II–Infused Hypertensive Rats With Kidney Injury

Jing Shao, Masaomi Nangaku, Toshio Miyata, +4

Hypertension

HypertensionRenal PathologyImmunologyRenal InflammationAng Ii +18

Transdifferentiation of cultured tubular cells induced by hypoxia

Krissanapong Manotham, Tetsuhiro Tanaka, Makiko Matsumoto, +7

Kidney International

PhysiologyHypoxia (Medicine)Cell CultureTissue CultureMedicine +3