Marie‐José Blouin

Metformin improves healthspan and lifespan in mice

Alejandro Martín‐Montalvo, Evi M. Mercken, Sarah J. Mitchell et al. · Nature Communications · 2013 · 1.4K citations · Full text

Lifespan Extension, Longevity, Medicine +4

Biliary epithelial and hepatocytic cell lineage relationships in embryonic rat liver as determined by the differential expression of cytokeratins, alpha-fetoprotein, albumin, and cell surface-exposed components.

Lucie Germain, Marie‐José Blouin, Normand Marceau · PubMed · 1988 · 216 citations

Immunology, Pathology, Cell Culture +22

Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells

Mahvash Zakikhani, Marie‐José Blouin, Esther Piura et al. · Breast Cancer Research and Treatment · 2010 · 209 citations

Breast Oncology, Medicine, Breast Cancer Cells +9

Serine Deprivation Enhances Antineoplastic Activity of Biguanides

Simon‐Pierre Gravel, Laura Hulea, Nader Toban et al. · Cancer Research · 2014 · 143 citations · Full text

Serine Synthesis, Biochemistry, Medicine +12

Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides

Laura Hulea, Simon‐Pierre Gravel, Masahiro Morita et al. · Cell Metabolism · 2018 · 85 citations · Full text

Metabolic Network, Signal Transduction, Biochemistry +9