ScaleS: an optical clearing palette for biological imaging

Hiroshi Hama, Hiroyuki Hioki, Kana Namiki, +8

Nature Neuroscience

EngineeringBiomedical ImagingOptical Clearing PaletteBiophotonicsImaging +3

CHIP Is Associated with Parkin, a Gene Responsible for Familial Parkinson's Disease, and Enhances Its Ubiquitin Ligase Activity

Yuzuru Imai, Mariko Soda, Shigetsugu Hatakeyama, +4

Molecular Cell

Neurodegenerative DiseasesFamilial ParkinsonGeneticsDegenerative PathologyNeuroscience +5

Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau

Yoshitaka Tatebayashi, Tomohiro Miyasaka, Dehua Chui, +11

Proceedings of the National Academy of Sciences

Neurochemical BiomarkersSocial SciencesAlzheimer's DiseaseR406w Tau MutationMemory +14

New Insights on How Metals Disrupt Amyloid β-Aggregation and Their Effects on Amyloid-β Cytotoxicity

Yuji Yoshiike, Kentaro Tanemura, Ohoshi Murayama, +6

Journal of Biological Chemistry

Neurodegeneration with Tau Accumulation in a Transgenic Mouse Expressing V337M Human Tau

Kentaro Tanemura, Miyuki Murayama, Takumi Akagi, +5

Journal of Neuroscience

Transgenic Mouse ModelsNeurochemical BiomarkersSocial SciencesMutant Human TauTau Aggregations +14

Formation of Filamentous Tau Aggregations in Transgenic Mice Expressing V337M Human Tau

Kentaro Tanemura, Takumi Akagi, Miyuki Murayama, +11

Neurobiology of Disease

Knockout MouseSignal TransductionTransgenic Mouse ModelsNatural SciencesMolecular Biology +5

Aberrant Tau Phosphorylation by Glycogen Synthase Kinase-3β and JNK3 Induces Oligomeric Tau Fibrils in COS-7 Cells

Shinji Sato, Yoshitaka Tatebayashi, Takumi Akagi, +10

Journal of Biological Chemistry

Molecular BiologyCytoskeletonAberrant Tau PhosphorylationSignaling PathwayNeurofibrillary Tangles +16

Mitochondrial dysfunction and tau hyperphosphorylation in Ts1Cje, a mouse model for Down syndrome

Ebrahim Abdul Shukkur, Atsushi Shimohata, Takumi Akagi, +12

Human Molecular Genetics

l-Serine Deficiency Elicits Intracellular Accumulation of Cytotoxic Deoxysphingolipids and Lipid Body Formation

Kayoko Esaki, Tomoko Sayano, Chiaki Sonoda, +7

Journal of Biological Chemistry

Surface Structure of Amyloid-β Fibrils Contributes to Cytotoxicity

Yuji Yoshiike, Takumi Akagi, Akihiko Takashima

Biochemistry