Shigetsugu Hatakeyama

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

Kevin L. Lorick, Jane P. Jensen, Shengyun Fang et al. · Proceedings of the National Academy of Sciences · 1999 · 1.2K citations · Full text

Ring Finger-containing Protein, Protein Function, Protein Assembly +13

Phosphorylation‐dependent degradation of c‐Myc is mediated by the F‐box protein Fbw7

Masayoshi Yada, Shigetsugu Hatakeyama, Takumi Kamura et al. · The EMBO Journal · 2004 · 807 citations · Full text

U Box Proteins as a New Family of Ubiquitin-Protein Ligases

Shigetsugu Hatakeyama, Masayoshi Yada, Masaki Matsumoto et al. · Journal of Biological Chemistry · 2001 · 577 citations · Full text

Essential role for ZAP-70 in both positive and negative selection of thymocytes

Izumi Negishi, Noboru Motoyama, Kei-ichi Nakayama et al. · Nature · 1995 · 548 citations

Signal Transduction, Essential Role, Lymphocyte Development +8

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of β-catenin

Masatoshi Kitagawa, Shigetsugu Hatakeyama, Michiko Shirane et al. · The EMBO Journal · 1999 · 527 citations · Full text

Protein Function, Natural Sciences, Molecular Biology +3