Ohoshi Murayama

Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

Taiichi Katayama, Kazunori Imaizumi, Naoya Sato et al. · Nature Cell Biology · 1999 · 518 citations

Signal Transduction, Signaling Pathway, Protein Folding +11

Presenilin 1 associates with glycogen synthase kinase-3β and its substrate tau

Akihiko Takashima, Miyuki Murayama, Ohoshi Murayama et al. · Proceedings of the National Academy of Sciences · 1998 · 403 citations · Full text

Alterations in Glucose Metabolism Induce Hypothermia Leading to Tau Hyperphosphorylation through Differential Inhibition of Kinase and Phosphatase Activities: Implications for Alzheimer's Disease

Emmanuel Planel, Tomohiro Miyasaka, Thomas Launey et al. · Journal of Neuroscience · 2004 · 255 citations · Full text

Neurochemical Biomarkers, Tau Protein, Nft Densities +17

New Insights on How Metals Disrupt Amyloid β-Aggregation and Their Effects on Amyloid-β Cytotoxicity

Yuji Yoshiike, Kentaro Tanemura, Ohoshi Murayama et al. · Journal of Biological Chemistry · 2001 · 243 citations · Full text

Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100

Xiaoyan Sun, Shinji Sato, Ohoshi Murayama et al. · Neuroscience Letters · 2002 · 162 citations

Amyloid Secretion, Alzheimer's Disease, Biochemistry +4