Philip B. Hylemon

Deoxycholic Acid (DCA) Causes Ligand-independent Activation of Epidermal Growth Factor Receptor (EGFR) and FAS Receptor in Primary Hepatocytes: Inhibition of EGFR/Mitogen-activated Protein Kinase-Signaling Module Enhances DCA-induced Apoptosis

Liang Qiao, Elaine Studer, Kevin Leach et al. · Molecular Biology of the Cell · 2001 · 231 citations

Conjugates of ursodeoxycholate protect against cholestasis and hepatocellular necrosis caused by more hydrophobic bile salts

Douglas M. Heuman, A. Scott Mills, Janice D. McCall et al. · Gastroenterology · 1991 · 225 citations · Full text

Oxysterol, Hepatology, Biochemistry +11

Conjugates of ursodeoxycholate protect against cytotoxicity of more hydrophobic bile salts: In vitro studies in rat hepatocytes and human erythrocytes

Douglas M. Heuman, Michael W. Pandak, Philip B. Hylemon et al. · Hepatology · 1991 · 210 citations

Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation

Margaret A. Park, Guo Zhang, Aditi Pandya Martin et al. · Cancer Biology & Therapy · 2008 · 172 citations · Full text

Bile Acid Regulation of C/EBPβ, CREB, and c-Jun Function, via the Extracellular Signal-Regulated Kinase and c-Jun NH₂-Terminal Kinase Pathways, Modulates the Apoptotic Response of Hepatocytes

Liang Qiao, Song Iy Han, Youwen Fang et al. · Molecular and Cellular Biology · 2003 · 150 citations · Full text

Apoptosis, Immunology, Cell Death +22