Youwen Fang

Bile Acid Regulation of C/EBPβ, CREB, and c-Jun Function, via the Extracellular Signal-Regulated Kinase and c-Jun NH₂-Terminal Kinase Pathways, Modulates the Apoptotic Response of Hepatocytes

Liang Qiao, Song Iy Han, Youwen Fang et al. · Molecular and Cellular Biology · 2003 · 150 citations · Full text

Apoptosis, Immunology, Cell Death +22

Bile acids induce mitochondrial ROS, which promote activation of receptor tyrosine kinases and signaling pathways in rat hepatocytes

Youwen Fang, Song Iy Han, Clint Mitchell et al. · Hepatology · 2004 · 128 citations · Full text

Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin–sensitive mechanism in murine and human hepatocytes†

Paul Dent, Youwen Fang, Seema Gupta et al. · Hepatology · 2005 · 120 citations

HIV protease inhibitors activate the unfolded protein response and disrupt lipid metabolism in primary hepatocytes

Huiping Zhou, Emily C. Gurley, Sirikalaya Jarujaron et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 2006 · 101 citations

Hiv Protease Inhibitors, Immunology, Cell Death +19

Bile acids regulate hepatic gluconeogenic genes and farnesoid X receptor via Gαi-protein-coupled receptors and the AKT pathway

Risheng Cao, Zhumei Xu Cronk, Weibin Zha et al. · Journal of Lipid Research · 2010 · 71 citations · Full text

Gastrointestinal Pharmacology, Gastroenterology, Farnesoid X Receptor +24