Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy

Wei Shi, Dan Xiao, Lin Wang, +6

Cell Death and Disease

Apoptosis and Growth Inhibition in Malignant Lymphocytes After Treatment With Arsenic Trioxide at Clinically Achievable Concentrations

Xinhua Zhu, Y. Shen, Yongkui Jing, +13

JNCI Journal of the National Cancer Institute

Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia

Xun Cai, Y-L Shen, Qian Zhu, +10

Leukemia

MitophagyArsenic Trioxide-induced ApoptosisMitochondrial FunctionBiochemistryApoptosis +8

Rearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemia.

S J Chen, Arthur Zelent, Jianhua Tong, +6

Journal of Clinical Investigation

PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptors.

Z Chen, Fabien Guidez, Philippe Rousselot, +7

Proceedings of the National Academy of Sciences

Hematological MalignancySignal TransductionProtein ExpressionNatural SciencesMixed-phenotype Acute Leukemia +11

Adenovirus-mediated gene transfer of soluble vascular cell adhesion molecule to porcine interposition vein grafts.

S J Chen, James M. Wilson, David W.M. Muller

Circulation

Molecular cytogenetic characterization and clinical relevance of additional, complex and/or variant chromosome abnormalities in acute promyelocytic leukemia

Lan‐Ping Xu, W-L Zhao, S-M Xiong, +14

Leukemia

Hematological MalignancyChromatinCytogeneticsMixed-phenotype Acute LeukemiaGenetics +10

Tissue factors on acute promyelocytic leukemia and endothelial cells are differently regulated by retinoic acid, arsenic trioxide and chemotherapeutic agents

Jun Zhu, W.Z. Guo, Y-Y Yao, +11

Leukemia

Hematological MalignancyEndothelial CellsMixed-phenotype Acute LeukemiaMalignant Blood DisorderImmunology +10

A viral long terminal repeat in the interleukin 2 gene of a cell line that constitutively produces interleukin 2.

S J Chen, Nikki J. Holbrook, Kenneth F. Mitchell, +4

Proceedings of the National Academy of Sciences

ImmunologyImmunologic MechanismInflammationImmunogeneticsTranscriptional Regulation +14

Large active area superconducting single-nanowire photon detector with a 100 <i>μ</i>m diameter

Chaolin Lv, Hong Zhou, Hao Li, +7

Superconductor Science and Technology

PhotonicsPhotonic SensorEngineeringPhysicsLarge Active Area +7