S J Chen

Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy

Wei Shi, Dan Xiao, Lin Wang et al. · Cell Death and Disease · 2012 · 296 citations · Full text

Apoptosis and Growth Inhibition in Malignant Lymphocytes After Treatment With Arsenic Trioxide at Clinically Achievable Concentrations

Xinhua Zhu, Y. Shen, Yongkui Jing et al. · JNCI Journal of the National Cancer Institute · 1999 · 274 citations · Full text

Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia

Xun Cai, Y-L Shen, Qian Zhu et al. · Leukemia · 2000 · 259 citations

Mitophagy, Arsenic Trioxide-induced Apoptosis, Mitochondrial Function +10

Rearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemia.

S J Chen, Arthur Zelent, Jianhua Tong et al. · Journal of Clinical Investigation · 1993 · 222 citations · Full text

PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptors.

Z Chen, Fabien Guidez, Philippe Rousselot et al. · Proceedings of the National Academy of Sciences · 1994 · 174 citations

Hematological Malignancy, Signal Transduction, Protein Expression +13