Z Chen

Fusion between a novel Krüppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia.

Z Chen, Nigel J. Brand, A. Chen et al. · The EMBO Journal · 1993 · 655 citations · Full text

Hematological Malignancy, Genetics, Hematology +8

Rearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemia.

S J Chen, Arthur Zelent, Jianhua Tong et al. · Journal of Clinical Investigation · 1993 · 222 citations · Full text

PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptors.

Z Chen, Fabien Guidez, Philippe Rousselot et al. · Proceedings of the National Academy of Sciences · 1994 · 174 citations

Hematological Malignancy, Signal Transduction, Protein Expression +13

Clinical and cytogenetic features of 508 Chinese patients with myelodysplastic syndrome and comparison with those in Western countries

B Chen, W-L Zhao, Jie Jin et al. · Leukemia · 2005 · 121 citations

Hematological Malignancy, Myelodysplastic Syndrome, Bone Marrow Failure +8

Rapid induction of cAMP/PKA pathway during retinoic acid-induced acute promyelocytic leukemia cell differentiation

Qian Zhao, Jianguo Tao, Qian Zhu et al. · Leukemia · 2003 · 77 citations

Signal Transduction, Developmental Biology, Rapid Induction +8