Structure-based Design of a Low Molecular Weight, Nonphosphorus, Nonpeptide, and Highly Selective Inhibitor of Protein-tyrosine Phosphatase 1B

Lars Iversen, Henrik Sune Andersen, Sven Branner, +9

Journal of Biological Chemistry

Ptp1b Knockout MiceLow Molecular WeightBiochemistryRemarkable SelectivityNatural Sciences +10

REMOVAL OF t‐BUTYL AND t‐BUTOXYCARBONYL PROTECTING GROUPS WITH TRIFLUOROACETIC ACID

Behrend F. Lundt, Nils L. Johansen, Aage Vølund, +1

International journal of peptide & protein research

Chemical EngineeringBioorganic ChemistryEngineeringBiochemistrySeparation Science +10

Synthesis of Novel GABA Uptake Inhibitors. 3. Diaryloxime and Diarylvinyl Ether Derivatives of Nipecotic Acid and Guvacine as Anticonvulsant Agents

Lars J. S. Knutsen, Knud Erik Andersen, Jesper Lau, +10

Journal of Medicinal Chemistry

Nipecotic AcidPharmacotherapyGaba Uptake InhibitorPharmaceutical ChemistryMolecular Pharmacology +14

New β-Alanine Derivatives Are Orally Available Glucagon Receptor Antagonists

Jesper Lau, Carsten Behrens, Ulla G. Sidelmann, +11

Journal of Medicinal Chemistry

Molecular PharmacologyPotent Glucagon AntagonistBiochemistryG Protein-coupled ReceptorMedicine +11

Synthesis of Novel γ-Aminobutyric Acid (GABA) Uptake Inhibitors. 5. Preparation and Structure−Activity Studies of Tricyclic Analogues of Known GABA Uptake Inhibitors

Knud Erik Andersen, Jan L. Sørensen, Jesper Lau, +5

Journal of Medicinal Chemistry

Novel γ-Aminobutyric AcidTricyclic AnaloguesPharmaceutical ScienceNipecotic AcidPharmacotherapy +15

Synthesis of Novel GABA Uptake Inhibitors. 4. Bioisosteric Transformation and Successive Optimization of Known GABA Uptake Inhibitors Leading to a Series of Potent Anticonvulsant Drug Candidates

Knud Erik Andersen, Jan L. Sørensen, Per Olaf Huusfeldt, +6

Journal of Medicinal Chemistry

Medicinal ChemistrySuccessive OptimizationBiochemistryMedicineBioisosteric Transformation +12

Synthesis of novel GABA uptake inhibitors. part 6 : Preparation and evaluation of N-Ω asymmetrically substituted nipecotic acid derivatives

Knud Erik Andersen, Jesper Lau, Behrend F. Lundt, +4

Bioorganic & Medicinal Chemistry

Novel Orally Active Growth Hormone Secretagogues

Thomas K. Hansen, Michael Ankersen, Birgit Sehested Hansen, +9

Journal of Medicinal Chemistry

Animal PhysiologyGrowth Hormone-releasing CompoundsPituitary GlandGrowth HormoneBiochemistry +8

A New Series of Highly Potent Growth Hormone-Releasing Peptides Derived from Ipamorelin

Michael Ankersen, Nils L. Johansen, Kjeld Madsen, +9

Journal of Medicinal Chemistry

PharmacotherapyNew SeriesExperimental PharmacologyMedicinal ChemistryPharmacological Study +14

The synthesis of novel GABA uptake inhibitors. Part 2. Synthesis of 5-hydroxytiagabine, a human metabolite of the GABA reuptake inhibitor tiagabine

Knud Erik Andersen, Mikael Begtrup, Mukund S. Chorghade, +6

Tetrahedron

Medicinal ChemistryPharmaceutical ChemistryBiochemistryMedicineNatural Sciences +8