Lars J. S. Knutsen

Characterization of tiagabine (NO-328), a new potent and selective GABA uptake inhibitor

Erik B. Nielsen, Peter D. Suzdak, Knud Erik Andersen et al. · European Journal of Pharmacology · 1991 · 232 citations

Medicine, Medicinal Chemistry, Pharmacology +13

<i>(R)‐N</i>‐[4,4‐Bis(3‐Methyl‐2‐Thienyl)but‐3‐en‐1‐yl]Nipecotic Acid Binds with High Affinity to the Brain γ‐Aminobutyric Acid Uptake Carrier

Erik B. Nielsen, Ursula Sonnewald, Lars J. S. Knutsen et al. · Journal of Neurochemistry · 1990 · 228 citations

Life Sciences, Neuroscience, Pharmacology +5

NNC-711, a novel potent and selective γ-aminobutyric acid uptake inhibitor: pharmacological characterization

Peter D. Suzdak, Kristen Frederiksen, Knud Erik Andersen et al. · European Journal of Pharmacology · 1992 · 160 citations

Medicine, Medicinal Chemistry, Pharmacology +14

The synthesis of novel GABA uptake inhibitors. 1. Elucidation of the structure-activity studies leading to the choice of (R)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]-3-piperidinecarboxylic acid (Tiagabine) as an anticonvulsant drug candidate

Knud Erik Andersen, Frederik C. Groenwald, A. JOERGENSEN et al. · Journal of Medicinal Chemistry · 1993 · 151 citations

Medicine, Medicinal Chemistry, Pharmacology +10

Discovery and Characterization of 6-{4-[3-(<i>R</i>)-2-Methylpyrrolidin-1-yl)propoxy]phenyl}-2<i>H</i>-pyridazin-3-one (CEP-26401, Irdabisant): A Potent, Selective Histamine H₃Receptor Inverse Agonist

Robert L. Hudkins, Rita Raddatz, Ming Tao et al. · Journal of Medicinal Chemistry · 2011 · 68 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15