T Andoh

Antitumor bisdioxopiperazines inhibit yeast DNAtopoisomerase II by trapping the enzyme in the form of a closed proteinclamp.

Joaquím Roca, Ryoji Ishida, James M. Berger et al. · Proceedings of the National Academy of Sciences · 1994 · 351 citations · Full text

Molecular Biology, Antimicrobial Chemotherapy, Type Ii Dna +18

Inhibition of topoisomerase II by antitumor agents bis(2,6-dioxopiperazine) derivatives.

K Tanabe, Yoji Ikegami, Ryoji Ishida et al. · PubMed · 1991 · 297 citations

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Chemistry +14

Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I.

T Andoh, Kazuyuki Ishii, Yoshio Suzuki et al. · Proceedings of the National Academy of Sciences · 1987 · 288 citations · Full text

Chromatin, Genome Instability, Oncogenic Agent +14

Inhibition of DNA topoisomerase II by ICRF-193 induces polyploidization by uncoupling chromosome dynamics from other cell cycle events.

Ryoji Ishida, Makoto Sato, Tetsuharu Narita et al. · The Journal of Cell Biology · 1994 · 160 citations · Full text

Cytogenetics, Genetics, Molecular Biology +21

Supercoiled DNA folded by non-histone proteins in cultured mammalian cells

Toshinori Ide, Masaki Nakane, Kaijiro Anzai et al. · Nature · 1975 · 97 citations

Chromatin, Chromatin Structure, Chromatin Remodeling +9