Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas

Jun‐ichi Nakayama, Hidetoshi Tahara, Eiji Tahara, +7

Nature Genetics

Tumor BiologyHuman Normal FibroblastsOncogenic AgentMedicinePathology +8

Mitogenic signalling and the p16INK4a–Rb pathway cooperate to enforce irreversible cellular senescence

Akiko Takahashi, Naoko Ohtani, Kimi Yamakoshi, +7

Nature Cell Biology

Transcriptional RegulationP16ink4a–rb Pathway CooperateSignal TransductionDevelopmental BiologyCell Regulation +7

G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3′ telomeric overhang in cancer cells

Hidetoshi Tahara, Kazuo Shin‐ya, Hiroyuki Seimiya, +3

Oncogene

Anaphase Bridge FormationCell RegulationCell DivisionMedicineCell Interaction +9

Telomere Reduction in Human Liver Tissues with Age and Chronic Inflammation

Hiroshi Aikata, Hideki Takaishi, Yoshiiku Kawakami, +7

Experimental Cell Research

InflammationHepatologyMedicineLiver PhysiologyImmunology +10

Immuno-histochemical detection of human telomerase catalytic component, hTERT, in human colorectal tumor and non-tumor tissue sections

Hidetoshi Tahara, Wataru Yasui, E Tahara, +7

Oncogene

Immuno-histochemical DetectionMedicineNon-tumor Tissue SectionsPathologyColorectal Cancer +8

Microgravity Potentiates Stem Cell Proliferation While Sustaining the Capability of Differentiation

Louis Yuge, Teruyuki Kajiume, Hidetoshi Tahara, +8

Stem Cells and Development

Abnormal telomere dynamics of B-lymphoblastoid cell strains from Werner's syndrome patients transformed by Epstein – Barr virus

Hidetoshi Tahara, Yoshiki Tokutake, Shizuko Maeda, +9

Oncogene

Lymphoid NeoplasiaPathogenesisImmunologyPathologyVirology +6

G1P3, an interferon inducible gene 6-16, is expressed in gastric cancers and inhibits mitochondrial-mediated apoptosis in gastric cancer cell line TMK-1 cell

E Tahara, Hidetoshi Tahara, Masamoto Kanno, +9

Cancer Immunology Immunotherapy

MedicineApoptosisImmunologyCell DeathInhibits Mitochondrial-mediated Apoptosis +6

Supercoiled DNA folded by non-histone proteins in cultured mammalian cells

Toshinori Ide, Masaki Nakane, Kaijiro Anzai, +1

Nature

ChromatinChromatin StructureChromatin RemodelingNatural SciencesEpigenetic Change +7

High-Level Expression of the Mnb/Dyrk1A Gene in Brain and Heart during Rat Early Development

Michiyo Okui, Toshinori Ide, Keiichi Morita, +6

Genomics

Cardiac MuscleMnb/dyrk1a GeneCardiomyopathyMolecular NeuroscienceMolecular Physiology +10