Hiroshi Aikata

Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer

Akihiro Fujimoto, Mayuko Furuta, Yasushi Totoki et al. · Nature Genetics · 2016 · 703 citations

Whole-genome Mutational Landscape, Somatic Variant, Tumor Heterogeneity +10

Randomised, multicentre prospective trial of transarterial chemoembolisation (TACE) plus sorafenib as compared with TACE alone in patients with hepatocellular carcinoma: TACTICS trial

Masatoshi Kudo, Kazuomi Ueshima, Masafumi Ikeda et al. · Gut · 2019 · 686 citations · Full text

Lenvatinib plus pembrolizumab versus lenvatinib plus placebo for advanced hepatocellular carcinoma (LEAP-002): a randomised, double-blind, phase 3 trial

Josep M. Llovet, Masatoshi Kudo, Philippe Merle et al. · The Lancet Oncology · 2023 · 364 citations

Oncology, Hepatology, Medicine +10

Genomic characterization of biliary tract cancers identifies driver genes and predisposing mutations

Christopher P. Wardell, Masashi Fujita, Tōru Yamada et al. · Journal of Hepatology · 2018 · 361 citations · Full text

Sorafenib plus low-dose cisplatin and fluorouracil hepatic arterial infusion chemotherapy versus sorafenib alone in patients with advanced hepatocellular carcinoma (SILIUS): a randomised, open label, phase 3 trial

Masatoshi Kudo, Kazuomi Ueshima, Osamu Yokosuka et al. · ˜The œLancet. Gastroenterology & hepatology · 2018 · 303 citations

Hepatology, Medicine, Clinical Trials +10