Modulation of the endoplasmic reticulum–mitochondria interface in Alzheimer’s disease and related models

Louise Hedskog, Catarina Moreira Pinho, Riccardo Filadi, +14

Proceedings of the National Academy of Sciences

Cell DeathRelated ModelsMitochondrial BiologyAmyloid Precursor ProteinPhysical Contact +23

DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy

Kelly Jean Thomas Craig, Melissa K. McCoy, Jeff Blackinton, +7

Human Molecular Genetics

Dj-1 ActsMitophagyGeneticsMolecular BiologyCell Death +16

Mitochondrial Alterations in PINK1 Deficient Cells Are Influenced by Calcineurin-Dependent Dephosphorylation of Dynamin-Related Protein 1

Anna Sandebring, Kelly Jean Thomas Craig, Alexandra Beilina, +9

PLoS ONE

MitophagyMitochondrial DysfunctionMolecular BiologyCytoskeletonCellular Physiology +16

The Pathogenic Aβ43 Is Enriched in Familial and Sporadic Alzheimer Disease

Anna Sandebring, Hedvig Welander, Bengt Winblad, +2

PLoS ONE

Sporadic Alzheimer DiseaseGeneticsNeurochemical BiomarkersPeptide ScienceSynaptic Signaling +20

Parkin deficiency disrupts calcium homeostasis by modulating phospholipase C signalling

Anna Sandebring, Nodi Dehvari, Mónica Pérez‐Manso, +5

FEBS Journal

Ca2+ HomeostasisMitophagyParkin Deficiency DisruptsCell DeathCytoskeleton +16

Thioredoxin‐80 is a product of alpha‐secretase cleavage that inhibits amyloid‐beta aggregation and is decreased in Alzheimer's disease brain

Francisco J. Gil‐Bea, Susanne Akterin, Torbjörn Persson, +8

EMBO Molecular Medicine

Trx80 ProductionTrx80 GenerationNeurochemical BiomarkersAmyloid‐beta AggregationSynaptic Signaling +24

Identification of two novel synaptic γ-secretase associated proteins that affect amyloid β-peptide levels without altering Notch processing

Susanne Frykman, Yasuhiro Teranishi, Ji‐Yeun Hur, +9

Neurochemistry International

Notch ProcessingNeurodegenerative DiseasesProtein FunctionMolecular NeuroscienceNovel Synaptic γ-Secretase +9

Parkin- An E3 Ubiquitin Ligase with Multiple Substrates

Anna Sandebring

Journal of Alzheimer’s Disease & Parkinsonism

Neurodegenerative DiseasesProtein FunctionNeurobiology Of DiseaseClinical SymptomsE3 Ubiquitin Ligase +11

Parkin‐mediated ubiquitination regulates phospholipase C‐γ1

Nodi Dehvari, Anna Sandebring, Amilcar Flores‐Morales, +6

Journal of Cellular and Molecular Medicine