Élise Ghiro

Structure−Activity Study on a Novel Series of Macrocyclic Inhibitors of the Hepatitis C Virus NS3 Protease Leading to the Discovery of BILN 2061

Montse Llinàs‐Brunet, Murray D. Bailey, Gordon T. Bolger et al. · Journal of Medicinal Chemistry · 2004 · 186 citations

Competitive Hexapeptide Inhibitors, Pharmacotherapy, Antiviral Drug +16

A Systematic Approach to the Optimization of Substrate-Based Inhibitors of the Hepatitis C Virus NS3 Protease:  Discovery of Potent and Specific Tripeptide Inhibitors

Montse Llinàs‐Brunet, Murray D. Bailey, Élise Ghiro et al. · Journal of Medicinal Chemistry · 2004 · 122 citations · Full text

Peptide Substrates, Antiviral Drug, Chemical Biology +21

Highly potent and selective peptide-based inhibitors of the hepatitis C virus serine protease: towards smaller inhibitors

Montse Llinàs‐Brunet, Murray D. Bailey, Gulrez Fazal et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 108 citations · Full text

Biochemistry, Medicine, Antiviral Drug Development +9

Synthesis of BILN 2061, an HCV NS3 Protease Inhibitor with Proven Antiviral Effect in Humans

Anne‐Marie Faucher, Murray D. Bailey, Pierre L. Beaulieu et al. · Organic Letters · 2004 · 103 citations

Medicinal Chemistry, Ns3 Protease Inhibitor, Medicine +13

Discovery of a Potent and Selective Noncovalent Linear Inhibitor of the Hepatitis C Virus NS3 Protease (BI 201335)

Montse Llinàs‐Brunet, Murray D. Bailey, Nathalie Goudreau et al. · Journal of Medicinal Chemistry · 2010 · 89 citations