Craig Bryant

Orally Active Trifluoromethyl Ketone Inhibitors of Human Leukocyte Elastase

Chris A. Veale, Peter R Bernstein, Claudia Bohnert et al. · Journal of Medicinal Chemistry · 1997 · 70 citations · Full text

Medicinal Chemistry, Oral Bioavailability, Pharmaceutical Science +13

Nonpeptidic inhibitors of human leukocyte elastase. 5. Design, synthesis, and x-ray crystallography of a series of orally active 5-aminopyrimidin-6-one-containing trifluoromethyl ketones

Chris A. Veale, Peter R Bernstein, Craig Bryant et al. · Journal of Medicinal Chemistry · 1995 · 60 citations · Full text

X-ray Crystallography, Pharmaceutical Science, Drug Target +17

Non-peptidic inhibitors of human leukocyte elastase. 4. Design, synthesis, and in vitro and in vivo activity of a series of .beta.-carbolinone-containing trifluoromethyl ketones

Chris A. Veale, James Damewood, Gary B. Steelman et al. · Journal of Medicinal Chemistry · 1995 · 55 citations · Full text

Nonpeptidic Inhibitors of Human Leukocyte Elastase. 3. Design, Synthesis, X-ray Crystallographic Analysis, and Structure-Activity Relationships for a Series of Orally Active 3-Amino-6-phenyl-2-pyridinyl Trifluoromethyl Ketones

Peter R Bernstein, Donald W. Andisik, Prudence K. Bradley et al. · Journal of Medicinal Chemistry · 1994 · 54 citations · Full text

Pharmaceutical Science, Human Leukocyte Elastase, Pharmacotherapy +18

Design of Orally Active, Non-Peptidic Inhibitors of Human Leukocyte Elastase

Frederick J. Brown, Donald W. Andisik, Peter R Bernstein et al. · Journal of Medicinal Chemistry · 1994 · 48 citations · Full text

Immunology, Altmetric Attention Score, Pharmacotherapy +19