Stefano Norbedo

Small-Molecule Inhibitors of the MDM2-p53 Protein−Protein Interaction Based on an Isoindolinone Scaffold

Ian R. Hardcastle, Shafiq U. Ahmed, Helen Atkins et al. · Journal of Medicinal Chemistry · 2006 · 144 citations · Full text

Mdm2-p53 Interaction, Drug Target, Isoindolinone Scaffold +17

Isoindolinone-based inhibitors of the MDM2–p53 protein–protein interaction

Ian R. Hardcastle, Shafiq U. Ahmed, Helen Atkins et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 91 citations

Molecular Pharmacology, Biochemistry, Isoindolinone-based Inhibitors +7

Regio- and stereoselective ring opening of 2,3-epoxyalcohols with diethylaluminium azide

Fabio Benedetti, Federico Berti, Stefano Norbedo · Tetrahedron Letters · 1998 · 56 citations

Alkene Metathesis, Stereoselective Ring Opening, Organic Chemistry +3

Versatile and Stereoselective Synthesis of Diamino Diol Dipeptide Isosteres, Core Units of Pseudopeptide HIV Protease Inhibitors

Fabio Benedetti, Stanislav Miertuš, Stefano Norbedo et al. · The Journal of Organic Chemistry · 1997 · 38 citations

Medicinal Chemistry, Pharmaceutical Chemistry, Biochemistry +12

Facile inversion of configuration of N-Boc-β-aminoalcohols via SN2 cyclization to oxazolidinones

Fabio Benedetti, Stefano Norbedo · Tetrahedron Letters · 2000 · 36 citations

Combinatorial Chemistry, Engineering, Organic Chemistry +6