Shafiq U. Ahmed

Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma

Saverio Tardito, Anaïs Oudin, Shafiq U. Ahmed et al. · Nature Cell Biology · 2015 · 556 citations

Medicine, Cancer Biology, Oncology +14

Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death

Gabriel Ichim, Jonathan Lopez, Shafiq U. Ahmed et al. · Molecular Cell · 2015 · 469 citations · Full text

Life Sciences, Cell Biology, Oncology +13

Selective Inhibition of Parallel DNA Damage Response Pathways Optimizes Radiosensitization of Glioblastoma Stem-like Cells

Shafiq U. Ahmed, Ross Carruthers, Lesley Gilmour et al. · Cancer Research · 2015 · 194 citations

Medicine, Molecular Biology, Oncology +17

Replication Stress Drives Constitutive Activation of the DNA Damage Response and Radioresistance in Glioblastoma Stem-like Cells

Ross Carruthers, Shafiq U. Ahmed, Shaliny Ramachandran et al. · Cancer Research · 2018 · 188 citations · Full text

Medicine, Cancer Biology, Oncology +17

Isoindolinone Inhibitors of the Murine Double Minute 2 (MDM2)-p53 Protein−Protein Interaction: Structure−Activity Studies Leading to Improved Potency

Ian R. Hardcastle, Junfeng Liu, Eric Valeur et al. · Journal of Medicinal Chemistry · 2011 · 149 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +7