Shafiq U. Ahmed

Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma

Saverio Tardito, Anaïs Oudin, Shafiq U. Ahmed et al. · Nature Cell Biology · 2015 · 538 citations

Neuro-oncology, Biosynthesis, Engineering +6

Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death

Gabriel Ichim, Jonathan Lopez, Shafiq U. Ahmed et al. · Molecular Cell · 2015 · 449 citations · Full text

Mitophagy, Dna Damage, Genetics +17

Selective Inhibition of Parallel DNA Damage Response Pathways Optimizes Radiosensitization of Glioblastoma Stem-like Cells

Shafiq U. Ahmed, Ross Carruthers, Lesley Gilmour et al. · Cancer Research · 2015 · 188 citations

Selective Inhibition, Neuro-oncology, Radiation Oncology +13

Replication Stress Drives Constitutive Activation of the DNA Damage Response and Radioresistance in Glioblastoma Stem-like Cells

Ross Carruthers, Shafiq U. Ahmed, Shaliny Ramachandran et al. · Cancer Research · 2018 · 180 citations · Full text

Small-Molecule Inhibitors of the MDM2-p53 Protein−Protein Interaction Based on an Isoindolinone Scaffold

Ian R. Hardcastle, Shafiq U. Ahmed, Helen Atkins et al. · Journal of Medicinal Chemistry · 2006 · 144 citations · Full text

Mdm2-p53 Interaction, Drug Target, Isoindolinone Scaffold +17