Does age matter? The impact of rodent age on study outcomes

Samuel J. Jackson, Nick Andrews, D.I. Ball, +13

Laboratory Animals

AgingRodent EcologyBiogerontologyPsychologyLaboratory Animal Study +19

Salmeterol, a novel, long‐acting β₂‐adrenoceptor agonist: characterization of pharmacological activity<i>in vitro</i>and<i>in vivo</i>

D.I. Ball, R T Brittain, Robert A. Coleman, +7

British Journal of Pharmacology

Discovery of 6-Amino-2-{[(1<i>S</i>)-1-methylbutyl]oxy}-9-[5-(1-piperidinyl)pentyl]-7,9-dihydro-8<i>H</i>-purin-8-one (GSK2245035), a Highly Potent and Selective Intranasal Toll-Like Receptor 7 Agonist for the Treatment of Asthma

Keith Biggadike, Mahbub Ahmed, D.I. Ball, +23

Journal of Medicinal Chemistry

AsthmaInflammatory Lung DiseaseLung InflammationAllergy MedicineImmunology +27

Imaging drugs, metabolites and biomarkers in rodent lung: a DESI MS strategy for the evaluation of drug-induced lipidosis

Alex Dexter, Rory T. Steven, Aateka Patel, +7

Analytical and Bioanalytical Chemistry

The Identification of a Novel Phosphodiesterase 4 Inhibitor, 1-Ethyl-5-{5-[(4-methyl-1-piperazinyl)methyl]-1,3,4-oxadiazol-2-yl}-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-b]pyridin-4-amine (EPPA-1), with Improved Therapeutic Index using Pica Feeding in Rats as a Measure of Emetogenicity

Trong Davis, John J. Peterson, Jen-Pyng Kou, +12

Journal of Pharmacology and Experimental Therapeutics

Low molecular weight neurokinin NK2 antagonists

Paul W. Smith, Andrew B. McElroy, John M. Pritchard, +9

Bioorganic & Medicinal Chemistry Letters

MedicineImmunologyNeuropeptide ReceptorNeuropharmacologyPharmacotherapy +5

Morphometric Characterization of Rat and Human Alveolar Macrophage Cell Models and their Response to Amiodarone using High Content Image Analysis

Ewelina Hoffman, Aateka Patel, D.I. Ball, +8

Pharmaceutical Research

Characterisation of the Neurokinin Receptors Mediating Contraction of Isolated Tracheal Preparations from a Variety of Species

R L Sheldrick, D.I. Ball, R A Coleman

Birkhäuser Basel eBooks

Isolated Tracheal PreparationsTracheal Smooth MuscleImmunologyCellular PhysiologySubstance P +18

Comparison of Oral, Intranasal and Aerosol Administration of Amiodarone in Rats as a Model of Pulmonary Phospholipidosis

Aateka Patel, Ewelina Hoffman, D.I. Ball, +10

Pharmaceutics

A novel method for the evaluation of bronchoactive agents in the conscious guinea pig

D.I. Ball, Robert A. Coleman, Reginald Hartley, +1

Journal of Pharmacological Methods

Animal PhysiologyAsthmaNovel MethodMedicinePulmonary Pharmacology +6