Defective Mitochondrial Dynamics Is an Early Event in Skeletal Muscle of an Amyotrophic Lateral Sclerosis Mouse Model

Luo Guo, Jianxun Yi, Changling Ma, +4

PLoS ONE

Integrin α5 down-regulation by miR-205 suppresses triple negative breast cancer stemness and metastasis by inhibiting the Src/Vav2/Rac1 pathway

Yajuan Xiao, Yunfei Li, Hua Tao, +6

Cancer Letters

Breast OncologyEpigenetic RegulationMedicineStem CellsCancer Cell Biology +12

In vivo β-catenin attenuation by the integrin α5-targeting nano-delivery strategy suppresses triple negative breast cancer stemness and metastasis

Yunfei Li, Yajuan Xiao, Hsuan-Pei Lin, +7

Biomaterials

NanomedicineVivo β-Catenin AttenuationEngineeringBreast OncologyCell-matrix Interaction +9

ROS-related mitochondrial dysfunction in skeletal muscle of an ALS mouse model during the disease progression

Yajuan Xiao, Chehade N. Karam, Jianxun Yi, +10

Pharmacological Research

Mitochondrial MyopathyAmyotrophic Lateral SclerosisMitochondrial FunctionSkeletal MuscleAls Mouse Model +7

Integrin α9 depletion promotes β‐catenin degradation to suppress triple‐negative breast cancer tumor growth and metastasis

Zhishan Wang, Yunfei Li, Yajuan Xiao, +5

International Journal of Cancer

β‐Catenin DegradationBreast OncologyCancer BiologyMammary Gland DevelopmentTumor Biology +14

Suppressed autophagy flux in skeletal muscle of an amyotrophic lateral sclerosis mouse model during disease progression

Yajuan Xiao, Changling Ma, Jianxun Yi, +6

Physiological Reports

MitophagyDisease ProgressionCell DeathCellular PhysiologyCell Autophagy +15

ALS-associated mutation SOD1G93A leads to abnormal mitochondrial dynamics in osteocytes

Huan Wang, Jianxun Yi, Xuejun Li, +3

Bone

Amyotrophic Lateral SclerosisMitochondrial FunctionMitochondrial DynamicGeneticsMitochondrial Dynamics +5

Absence of physiological Ca2+ transients is an initial trigger for mitochondrial dysfunction in skeletal muscle following denervation

Chehade N. Karam, Jianxun Yi, Yajuan Xiao, +9

Skeletal Muscle

Impaired Bone Homeostasis in Amyotrophic Lateral Sclerosis Mice with Muscle Atrophy

Ke Zhu, Jianxun Yi, Yajuan Xiao, +9

Journal of Biological Chemistry

Neurodegenerative DiseasesSclerostinAmyotrophic Lateral SclerosisHealth SciencesGenetics +13

Inhibition of Siah2 Ubiquitin Ligase by Vitamin K3 Attenuates Chronic Myeloid Leukemia Chemo-Resistance in Hypoxic Microenvironment

Jixian Huang, Ziyuan Lu, Yajuan Xiao, +5

Medical Science Monitor