Chuan-En Wang

Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms

Jennifer W. Bradford, Ji‐Yeon Shin, Meredith Roberts et al. · Proceedings of the National Academy of Sciences · 2009 · 353 citations · Full text

Neural Stem Cell, Social Sciences, Mutant Huntingtin +17

Polyglutamine expansion of huntingtin impairs its nuclear export

Jonathan Cornett, Fengli Cao, Chuan-En Wang et al. · Nature Genetics · 2005 · 186 citations

Biochemistry, Natural Sciences, Biochemical Genetics +3

Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease

Chuan-En Wang, Suzanne Tydlacka, Adam L. Orr et al. · Human Molecular Genetics · 2008 · 160 citations · Full text

N-terminal Mutant Huntingtin, Monkey Models, Genetics +18

Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice

Guoqing Sheng, Xingshun Xu, Yung‐Feng Lin et al. · Journal of Clinical Investigation · 2008 · 91 citations · Full text

Knockout Mouse, Mouse Ahi1, Brainstem Development +15

Species-dependent neuropathology in transgenic SOD1 pigs

Huaqiang Yang, Guohao Wang, Haitao Sun et al. · Cell Research · 2014 · 52 citations · Full text

Animal Science, Genetics, Transgenic Sod1 Pigs +4