Huaqiang Yang

A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington’s Disease

Sen Yan, Zhuchi Tu, Zhaoming Liu et al. · Cell · 2018 · 330 citations

Knockout Mouse, Neurodegenerative Diseases, Neurobiology Of Disease +13

Generation of CRISPR/Cas9-mediated gene-targeted pigs via somatic cell nuclear transfer

Xiaoqing Zhou, Jige Xin, Nana Fan et al. · Cellular and Molecular Life Sciences · 2014 · 247 citations · Full text

Engineering, Somatic Cell Genetics, Genetic Engineering +10

Expression of Huntington's disease protein results in apoptotic neurons in the brains of cloned transgenic pigs

Dongshan Yang, Chuan-En Wang, Bentian Zhao et al. · Human Molecular Genetics · 2010 · 152 citations · Full text

Transgenic Mouse Models, Genetics, Cell Death +22

CD163 knockout pigs are fully resistant to highly pathogenic porcine reproductive and respiratory syndrome virus

Huaqiang Yang, Jian Zhang, Xianwei Zhang et al. · Antiviral Research · 2018 · 140 citations

Pathogenesis, Viral Pathogenesis, Pathology +9

Small molecules enhance CRISPR/Cas9-mediated homology-directed genome editing in primary cells

Guoling Li, Xianwei Zhang, Cuili Zhong et al. · Scientific Reports · 2017 · 137 citations · Full text