Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms

Jennifer W. Bradford, Ji‐Yeon Shin, Meredith Roberts, +3

Proceedings of the National Academy of Sciences

Neural Stem CellSocial SciencesMutant HuntingtinNeuroinflammationDegenerative Pathology +15

Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells

Nathan J. Palpant, Lil Pabon, Clayton E. Friedman, +6

Nature Protocols

Tissue EngineeringRegenerative MedicineHigh-purity CardiacInduced Pluripotent Stem CellCardiac Reprogramming +13

Mutant Huntingtin in Glial Cells Exacerbates Neurological Symptoms of Huntington Disease Mice

Jennifer W. Bradford, Ji‐Yeon Shin, Meredith Roberts, +4

Journal of Biological Chemistry

Knockout MouseNeurodegenerative DiseasesMedicineGeneticsDegenerative Disease +12

SCFSlimb ubiquitin ligase suppresses condensin II–mediated nuclear reorganization by degrading Cap-H2

Daniel W. Buster, Scott G. Daniel, Huy Q. Nguyen, +10

The Journal of Cell Biology

Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes

Nathan J. Palpant, Lil Pabon, Meredith Roberts, +8

Development

Stromal Cells in Dense Collagen Promote Cardiomyocyte and Microvascular Patterning in Engineered Human Heart Tissue

Meredith Roberts, Dominic M. D. Tran, Kareen L. K. Coulombe, +4

Tissue Engineering Part A

Tissue EngineeringStromal CellsCardiac MuscleEngineeringBiomaterials Design +25

Transcriptional dysregulation of TrkA associates with neurodegeneration in spinocerebellar ataxia type 17

Anjali G. Shah, Mark J. Friedman, Shanshan Huang, +3

Human Molecular Genetics

GeneticsUniversal Transcription FactorTranscriptional RegulationExperimental NeuropathologyDegenerative Pathology +14

Maintenance of Interphase Chromosome Compaction and Homolog Pairing in <i>Drosophila</i> Is Regulated by the Condensin Cap-H2 and Its Partner Mrg15

Helen Smith, Meredith Roberts, Huy Q. Nguyen, +6

Genetics

Sex-dependent Effect of BAG1 in Ameliorating Motor Deficits of Huntington Disease Transgenic Mice

Adam L. Orr, Shanshan Huang, Meredith Roberts, +3

Journal of Biological Chemistry

Knockout MouseSex-dependent EffectNatural SciencesGeneticsGenetic Disorder +13

Glutamatergic metabolites are associated with visual plasticity in humans

S. Andrea Wijtenburg, Jeffrey West, Stephanie A. Korenic, +7

Neuroscience Letters

Synaptic PlasticityNeurophysiologyVisual PlasticityNeuroscienceVisual Pathway +4