Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer’s disease pathology

Hansruedi Mathys, Zhuyu Peng, Carles A. Boix, +27

Cell

Conserved nucleosome positioning defines replication origins

Matthew L. Eaton, Kyriaki Galani, Sukhyun Kang, +2

Genes & Development

GeneticsGenomic MechanismMolecular BiologyMolecular GeneticsGenomics +15

Human microglial state dynamics in Alzheimer’s disease progression

Na Sun, Matheus B. Victor, Yongjin Park, +16

Cell

Single-cell dissection of the human brain vasculature

F. García, Na Sun, Hyeseung Lee, +12

Nature

Single-cell DissectionNeuroanatomyInterdisciplinary NeurosurgeryCerebral OrganoidNeuroscience +5

Single-cell multiregion dissection of Alzheimer’s disease

Hansruedi Mathys, Carles A. Boix, Leyla Anne Akay, +17

Nature

Mechanochemical Removal of Ribosome Biogenesis Factors from Nascent 60S Ribosomal Subunits

Cornelia Ulbrich, Meikel Diepholz, Jochen Baßler, +5

Cell

Ribosome Biogenesis FactorsNascent 60SBiochemistryNatural SciencesRibosomal Subunits +6

Epigenomic dissection of Alzheimer’s disease pinpoints causal variants and reveals epigenome erosion

Xushen Xiong, Benjamin T. James, Carles A. Boix, +14

Cell

Mec1 Is One of Multiple Kinases that Prime the Mcm2-7 Helicase for Phosphorylation by Cdc7

John C.W. Randell, Andy C. Fan, Clara S. Chan, +4

Molecular Cell

Protein FunctionSignal TransductionCell RegulationMolecular BiologyMcm2-7 Helicase +5

Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer’s disease

Na Sun, Leyla Anne Akay, Mitchell H. Murdock, +10

Nature Neuroscience

Neuroimaging BiomarkersNeurodegenerative DiseasesMolecular NeuroscienceAlzheimer's DiseaseNeuroimaging +8

Rea1, a Dynein-related Nuclear AAA-ATPase, Is Involved in Late rRNA Processing and Nuclear Export of 60 S Subunits

Kyriaki Galani, Tracy Nissan, Elisabeth Petfalski, +2

Journal of Biological Chemistry

:Rea1 StrainMolecular BiologyCytoskeletonMolecular GeneticsProtein Synthesis +15