Hansruedi Mathys

Single-cell transcriptomic analysis of Alzheimer’s disease

Hansruedi Mathys, José Dávila-Velderrain, Zhuyu Peng et al. · Nature · 2019 · 2.5K citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Alzheimer's Disease +7

APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes

Joel Blanchard, Leyla Anne Akay, José Dávila-Velderrain et al. · Nature · 2022 · 460 citations · Full text

Oxysterol, Physiology, Degenerative Pathology +6

Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer’s disease pathology

Hansruedi Mathys, Zhuyu Peng, Carles A. Boix et al. · Cell · 2023 · 424 citations · Full text

Single-cell dissection of the human brain vasculature

F. García, Na Sun, Hyeseung Lee et al. · Nature · 2022 · 317 citations · Full text

Single-cell Dissection, Neuroanatomy, Interdisciplinary Neurosurgery +7

Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes

Joel Blanchard, Michael Bula, José Dávila-Velderrain et al. · Nature Medicine · 2020 · 283 citations · Full text

Human Blood–brain Barrier, Blood–brain Barrier, Immunology +10