An adenosine nucleoside inhibitor of dengue virus

Zheng Yin, Yen‐Liang Chen, Wouter Schul, +30

Proceedings of the National Academy of Sciences

Dengue VirusMolecular VirologyMedicineImmunologyAntiviral Therapy +7

PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 3: Comparative assessement of prediction methods of human clearance

Barbara J. Ring, Jenny Y. Chien, Kimberly K. Adkison, +15

Journal of Pharmaceutical Sciences

Pharmacokinetic ModelingMedicineDrug DiscoveryPrediction MethodsPhrma Cpcdc Initiative +6

PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: Prediction of plasma concentration–time profiles in human by using the physiologically‐based pharmacokinetic modeling approach

Patrick Poulin, Rhys D.O. Jones, Hannah M. Jones, +15

Journal of Pharmaceutical Sciences

Precision DosingPhysiologically Based PharmacokineticsPharmacokinetic ModelingHuman PharmacokineticsMedicine +7

Absorption, Metabolism, and Excretion of [14C]Vildagliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, in Humans

Handan He, Phi Tran, Hequn Yin, +8

Drug Metabolism and Disposition

PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 2: Comparative assessment of prediction methods of human volume of distribution

Rhys D.O. Jones, Hannah M. Jones, Malcolm Rowland, +15

Journal of Pharmaceutical Sciences

Translational MedicinePharmacokinetic ModelingPart 2Prediction MethodsMedicine +9

Development of clinical dosage forms for a poorly water soluble drug I: Application of polyethylene glycol–polysorbate 80 solid dispersion carrier system

Rose‐Marie Dannenfelser, Handan He, Yatindra M. Joshi, +2

Journal of Pharmaceutical Sciences

Pharmaceutical ScienceEngineeringPolyethylene Glycol–polysorbate 80ExcipientsMedicine +10

The Identification of Indacaterol as an Ultralong-Acting Inhaled β₂-Adrenoceptor Agonist

François Baur, David T. Beattie, David Beer, +31

Journal of Medicinal Chemistry

AsthmaMolecular PharmacologyTargeted Intermediate PotencyPulmonary CirculationVivo Profiling +9

Applications of Quantitative Systems Pharmacology in Model‐Informed Drug Discovery: Perspective on Impact and Opportunities

Erica L. Bradshaw, Mary E. Spilker, Richard Zang, +11

CPT Pharmacometrics & Systems Pharmacology

Inhibition of Dengue Virus RNA Synthesis by an Adenosine Nucleoside

Yen‐Liang Chen, Zheng Yin, Jeyaraj Duraiswamy, +16

Antimicrobial Agents and Chemotherapy

A Simplified PBPK Modeling Approach for Prediction of Pharmacokinetics of Four Primarily Renally Excreted and CYP3A Metabolized Compounds During Pregnancy

Binfeng Xia, Tycho Heimbach, Rakesh Gollen, +2

The AAPS Journal

Cyp3a Metabolized CompoundsPharmacokinetic ModelingPreclinical Drug EvaluationMedicineMaternal Health +6