Hiromasa Hashimoto

Benzimidazole Derivatives Bearing Substituted Biphenyls as Hepatitis C Virus NS5B RNA-Dependent RNA Polymerase Inhibitors:  Structure−Activity Relationship Studies and Identification of a Potent and Highly Selective Inhibitor JTK-109

Shintaro Hirashima, Takayoshi Suzuki, Tomio Ishida et al. · Journal of Medicinal Chemistry · 2006 · 146 citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Bioorganic Chemistry +15

Benzimidazole inhibitors of hepatitis C virus NS5B polymerase: Identification of 2-[(4-diarylmethoxy)phenyl]-benzimidazole

Tomio Ishida, Takayoshi Suzuki, Shintaro Hirashima et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 129 citations · Full text

Biochemistry, Medicine, Antiviral Drug Development +8

4-(4-Cycloalkyl/aryl-oxazol-5-yl)benzenesulfonamides as Selective Cyclooxygenase-2 Inhibitors:  Enhancement of the Selectivity by Introduction of a Fluorine Atom and Identification of a Potent, Highly Selective, and Orally Active COX-2 Inhibitor JTE-522

Hiromasa Hashimoto, Katsuaki Imamura, Jun‐ichi Haruta et al. · Journal of Medicinal Chemistry · 2002 · 121 citations · Full text

Bioorganic Chemistry, Pharmacotherapy, Selective Cyclooxygenase-2 Inhibitors +17

Discovery of Conformationally Constrained Tetracyclic Compounds as Potent Hepatitis C Virus NS5B RNA Polymerase Inhibitors

Kazutaka Ikegashira, Takahiro Oka, Shintaro Hirashima et al. · Journal of Medicinal Chemistry · 2006 · 110 citations · Full text

Combinatorial Chemistry, Biochemistry, Medicine +11

Zwitterionic DNA

Hiromasa Hashimoto, Marek G. Nelson, Christopher Switzer · Journal of the American Chemical Society · 1993 · 64 citations

Engineering, Databases, Altmetric Attention Score +16