Concepedia
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Publications
9
Citations
898
Authors
2
Location
San Diego, United States
Orphagen Pharmaceuticals (United States) is a company institution in San Diego, United States known for small molecules, immunology, and medicine.
Top concepts
MedicineImmunologyBiochemistryInflammationPharmacologyDrug DiscoverySmall MoleculesChemical BiologyDrug DevelopmentNatural Sciences
SAR Exploration Guided by LE and Fsp <sup>3</sup> : Discovery of a Selective and Orally Efficacious RORγ Inhibitor
Kazuyuki Hirata, Masayuki Kotoku, Noriyoshi Seki et al. · ACS Medicinal Chemistry Letters · 2015 · 58 citations · Full text
Discovery of Second Generation RORγ Inhibitors Composed of an Azole Scaffold
Masayuki Kotoku, Takaki Maeba, Shingo Fujioka et al. · Journal of Medicinal Chemistry · 2019 · 31 citations · Full text
Butanoic Acid Scaffold, Immunology, Chemical Biology +20
Ternary complex of human <scp>ROR</scp>γ ligand‐binding domain, inverse agonist and <scp>SMRT</scp> peptide shows a unique mechanism of corepressor recruitment
Masato Noguchi, Akihiro Nomura, Ken Murase et al. · Genes to Cells · 2017 · 27 citations · Full text
Ternary crystal structure of human RORγ ligand-binding-domain, an inhibitor and corepressor peptide provides a new insight into corepressor interaction
Masato Noguchi, Akihiro Nomura, Satoki Doi et al. · Scientific Reports · 2018 · 18 citations · Full text
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Orphagen Pharmaceuticals (United States), United States
5 publications · 101 citations
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5 publications · 91 citations
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