B3(Fv)-PE38KDEL, a single-chain immunotoxin that causes complete regression of a human carcinoma in mice.

Ulrich Brinkmann, Lee H. Pai, D J FitzGerald, +2

Proceedings of the National Academy of Sciences

ImmunotoxicologyImmunologyPathologyEscherichia ColiImmunologic Mechanism +21

Treatment of advanced solid tumors with immunotoxin LMB–1: An antibody linked to Pseudomonas exotoxin

Lee H. Pai, Robert E. Wittes, Ann Setser, +2

Nature Medicine

Microbial ToxinMedicineImmunologyTumor ImmunityPathology +5

Transforming growth factor-beta1 circulates in normal human plasma and is unchanged in advanced metastatic breast cancer.

Lalage M. Wakefield, John J. Letterio, T Chen, +7

PubMed

Breast OncologyNormal Human PlasmaImmunologyPathologyNormal Human Subjects +16

Monoclonal Antibody K1 Reacts With Epithelial Mesothelioma but not With Lung Adenocarcinoma

Kai Chang, Lee H. Pai, Harvey I. Pass, +4

The American Journal of Surgical Pathology

Murine Monoclonal AntibodyTumoral PathologyLung AdenocarcinomaImmunologyHistopathology +11

Characterization of the antigen (CAK1) recognized by monoclonal antibody K1 present on ovarian cancers and normal mesothelium.

Kai Chang, Lee H. Pai, Janendra K. Batra, +2

PubMed

Immunocytochemical TechniqueImmunologyPathologyAntigen ProcessingImmunotherapy +20

Evaluation of the serum stability and in vivo biodistribution of CHX-DTPA and other ligands for yttrium labeling of monoclonal antibodies.

Luigi Camera, Seigo Kinuya, Kayhan Garmestani, +7

PubMed

Anti-tumor activities of immunotoxins made of monoclonal antibody B3 and various forms of Pseudomonas exotoxin.

Lee H. Pai, Janendra K. Batra, David J. FitzGerald, +2

Proceedings of the National Academy of Sciences

Microbial ToxinAllergyImmunotoxicologyAnti-tumor ActivitiesImmunology +12

Antitumor activity of a transforming growth factor alpha-Pseudomonas exotoxin fusion protein (TGF-alpha-PE40).

Lee H. Pai, Maria Gallo, David J. FitzGerald, +1

PubMed

Microbial ToxinAntitumor ActivityImmunologyPseudomonas ToxinPathology +10

Immunotoxins containing Pseudomonas exotoxin that target LeY damage human endothelial cells in an antibody-specific mode: relevance to vascular leak syndrome.

Chien‐Tsun Kuan, Lee H. Pai, Ira Pastan

PubMed

ImmunologyPathologyVascular Leak SyndromeImmunotherapyPseudomonas Exotoxin +17

Inhibition of antibody response to Pseudomonas exotoxin and an immunotoxin containing Pseudomonas exotoxin by 15-deoxyspergualin in mice.

Lee H. Pai, David J. FitzGerald, Mark A. Tepper, +3

PubMed

Male Bdf1 MiceMicrobial ToxinAntimicrobial SusceptibilityAllergyImmunotoxicology +10