Alexander C. Weymouth‐Wilson

Looking glass inhibitors: scalable syntheses of DNJ, DMDP, and (3R)-3-hydroxy-l-bulgecinine from d-glucuronolactone and of l-DNJ, l-DMDP, and (3S)-3-hydroxy-d-bulgecinine from l-glucuronolactone. DMDP inhibits β-glucosidases and β-galactosidases whereas l-DMDP is a potent and specific inhibitor of α-glucosidases

Daniel Best, Chen Wang, Alexander C. Weymouth‐Wilson et al. · Tetrahedron Asymmetry · 2010 · 54 citations

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +13

<i>C</i>-Branched Iminosugars: α-Glucosidase Inhibition by Enantiomers of isoDMDP, isoDGDP, and isoDAB–<scp>l</scp>-isoDMDP Compared to Miglitol and Miglustat

Sarah F. Jenkinson, Daniel Best, A. Waldo Saville et al. · The Journal of Organic Chemistry · 2013 · 48 citations · Full text

Molecular Pharmacology, Pharmaceutical Science, Biosynthesis +15

Enantioselective synthesis of tetrafluorinated ribose and fructose

Bruno Linclau, A. James Boydell, Roxana S. Timofte et al. · Organic & Biomolecular Chemistry · 2009 · 41 citations

Pyranose Form, Engineering, Cyclisation Approach +9

Inhibition of Nonmammalian Glycosidases by Azetidine Iminosugars Derived from Stable 3,5-Di-<i>O</i>-triflates of Pentoses

Gabriel M. J. Lenagh‐Snow, Noelia Araújo, Sarah F. Jenkinson et al. · Organic Letters · 2011 · 39 citations

Specific Inhibition, Pharmaceutical Chemistry, Bioorganic Chemistry +13

Glycosidase Inhibition by All 10 Stereoisomeric 2,5-Dideoxy-2,5-iminohexitols Prepared from the Enantiomers of Glucuronolactone

Benjamin James Ayers, Nigel Ngo, Sarah F. Jenkinson et al. · The Journal of Organic Chemistry · 2012 · 36 citations

Bioorganic Chemistry, Glycobiology, Glycosidase Inhibition +16