Bruno Linclau

Systematic Investigation of Lipophilicity Modulation by Aliphatic Fluorination Motifs

Benjamin Jeffries, Zhong Wang, Hannah R. Felstead et al. · Journal of Medicinal Chemistry · 2020 · 154 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +17

Investigating the Influence of (Deoxy)fluorination on the Lipophilicity of Non‐UV‐Active Fluorinated Alkanols and Carbohydrates by a New log <i>P</i> Determination Method

Bruno Linclau, Zhong Wang, Guillaume Compain et al. · Angewandte Chemie International Edition · 2015 · 142 citations · Full text

Pharmacy, Chemistry, Analytical Chemistry +7

Reducing the Lipophilicity of Perfluoroalkyl Groups by CF₂–F/CF₂–Me or CF₃/CH₃ Exchange

Benjamin Jeffries, Zhong Wang, Jérôme Graton et al. · Journal of Medicinal Chemistry · 2018 · 112 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

An Unexpected and Significantly Lower Hydrogen‐Bond‐Donating Capacity of Fluorohydrins Compared to Nonfluorinated Alcohols

Jérôme Graton, Zhong Wang, Anne‐Marie Brossard et al. · Angewandte Chemie International Edition · 2012 · 93 citations · Full text

Natural Sciences, Chemistry, Organic Chemistry +5

Structural Basis of Ligand Binding to UDP-Galactopyranose Mutase from <i>Mycobacterium tuberculosis</i> Using Substrate and Tetrafluorinated Substrate Analogues

K.E. Van Straaten, Jijin R. A. Kuttiyatveetil, Charlotte M. Sevrain et al. · Journal of the American Chemical Society · 2015 · 83 citations · Full text

Life Sciences, Biochemistry, Microbiology +16