K.‐Fr. Sewing

Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat.

Martin Sattler, F. Peter Guengerich, Chul‐Ho Yun et al. · Drug Metabolism and Disposition · 1992 · 389 citations

Medicine, Biochemistry, Pharmacology +17

Metabolism of the immunosuppressant tacrolimus in the small intestine: cytochrome P450, drug interactions, and interindividual variability.

Alfonso Lampen, Uwe Christians, F. Peter Guengerich et al. · Drug Metabolism and Disposition · 1995 · 273 citations

Medicine, Pharmacokinetics, Pharmacology +17

Helicobacter pylori causes DNA damage in gastric epithelial cells

Barbara Obst, Siegfried Wagner, K.‐Fr. Sewing et al. · Carcinogenesis · 2000 · 177 citations

Medicine, Microbiology, Molecular Biology +15

Sensitive and specific quantification of sirolimus (rapamycin) and its metabolites in blood of kidney graft recipients by HPLC/electrospray-mass spectrometry

Frank Streit, Uwe Christians, Hans‐Martin Schiebel et al. · Clinical Chemistry · 1996 · 116 citations · Full text

Pharmacy, Pharmaceutical Analysis, Pharmacology +17

Effects of flavonoids on parietal cell acid secretion, gastric mucosal prostaglandin production and Helicobacter pylori growth.

Winfried Beil, C. Birkholz, K.‐Fr. Sewing · PubMed · 1995 · 95 citations

Medicine, Biochemistry, Pharmacology +13