Uwe Christians

Prolonged diabetes reversal after intraportal xenotransplantation of wild-type porcine islets in immunosuppressed nonhuman primates

Bernhard J. Hering, Martin Wijkstrom, Melanie L. Graham et al. · Nature Medicine · 2006 · 543 citations

Intraportal Xenotransplantation, Islet Transplantation, Xenotransplantation +8

Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat.

Martin Sattler, F. Peter Guengerich, Chul‐Ho Yun et al. · Drug Metabolism and Disposition · 1992 · 389 citations

Comparison of the Effects of Tacrolimus and Cyclosporine on the Pharmacokinetics of Mycophenolic Acid

Teun van Gelder, J Klupp, M.J. Barten et al. · Therapeutic Drug Monitoring · 2001 · 333 citations

Metabolism of the immunosuppressant tacrolimus in the small intestine: cytochrome P450, drug interactions, and interindividual variability.

Alfonso Lampen, Uwe Christians, F. Peter Guengerich et al. · Drug Metabolism and Disposition · 1995 · 273 citations

Lactonization Is the Critical First Step in the Disposition of the 3-Hydroxy-3-Methylglutaryl-Coa Reductase Inhibitor Atorvastatin

Wolfgang Jacobsen, Bernd Kuhn, Andrea Soldner et al. · Drug Metabolism and Disposition · 2000 · 233 citations