Charles E. Nichols - Concepedia

Author

Charles E. Nichols

Centre for Human Genetics

Also Known As

Charles E. Nichols, Charles Nichols

Publications

571

Citations

H-Index

Concepts

All Affiliations

Centre for Human Genetics University of Oxford Newcastle University Rutgers, The State University of New Jersey University of Alberta

About

Charles E. Nichols is an author at Centre for Human Genetics specializing in molecular biology, medicine, and structural biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	7	7	329
2	Natural Sciences	6	6	292
3	Biochemistry	4	4	216
4	Biomolecular Engineering	1	1	66
5	Chemical Biology	1	1	32

Charles E. Nichols

Publications

569

Citations

H-Index

Page 1

	Year	Citations
Binding of the Second Generation Non-nucleoside Inhibitor S-1153 to HIV-1 Reverse Transcriptase Involves Extensive Main Chain Hydrogen Bonding Jingshan Ren, Charles E. Nichols, Louise E. Bird, Journal of Biological Chemistry Crystal StructureViral ReplicationBiochemistryNatural SciencesHuman Retrovirus	2000	121
Structures, functions and adaptations of the human LINE-1 ORF2 protein Eric T. Baldwin, Trevor van Eeuwen, David Hoyos, Nature	2023	107
Relationship of Potency and Resilience to Drug Resistant Mutations for GW420867X Revealed by Crystal Structures of Inhibitor Complexes for Wild-Type, Leu100Ile, Lys101Glu, and Tyr188Cys Mutant HIV-1 Reverse Transcriptases Jingshan Ren, Charles E. Nichols, Philip P. Chamberlain, Journal of Medicinal Chemistry Inhibitor ComplexesMolecular BiologyAntiviral DrugMedicinal ChemistryHuman Retrovirus	2007	66
Structural insights into mechanisms of non‐nucleoside drug resistance for HIV‐1 reverse transcriptases mutated at codons 101 or 138 Jingshan Ren, Charles E. Nichols, Anna Stamp, FEBS Journal	2006	55
Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K–specific inhibition Eric T. Baldwin, Matthias Götte, Egor P. Tchesnokov, Proceedings of the National Academy of Sciences Crystal StructureViral ReplicationViral Polymerase MechanismImmunologyMolecular Biology	2022	37
Crystallographic studies of shikimate binding and induced conformational changes in <i>Mycobacterium tuberculosis</i> shikimate kinase B. Dhaliwal, Charles E. Nichols, Jingshan Ren, FEBS Letters	2004	34
Functional analysis of the GTPases EngA and YhbZ encoded by<i>Salmonella typhimurium</i> Heather K. Lamb, Paul M. Thompson, Catherine Elliott, Protein Science Structural BioinformaticsBiomolecular Structure PredictionMolecular BiologyEscherichia ColiNormal Ribosome Maturation	2007	34
Structures of <i>S. aureus</i> thymidylate kinase reveal an atypical active site configuration and an intermediate conformational state upon substrate binding Masayo Kotaka, B. Dhaliwal, Jingshan Ren, Protein Science Protein AssemblyBiomolecular Structure PredictionStructural BioinformaticsMolecular BiologyChemical Biology	2006	32
Crystal Structure of CC3 (TIP30) Kamel El Omari, Louise E. Bird, Charles E. Nichols, Journal of Biological Chemistry	2005	31
Structural and functional characterization of <i>Salmonella enterica</i> serovar Typhimurium YcbL: An unusual Type II glyoxalase Anna Stamp, Paul Owen, Kamel El Omari, Protein Science Typhimurium YcblMolecular BiologyAnalytical UltracentrifugationYcbl StructureProtein X-ray Crystallography	2010	29

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