Jens M. Seeger

Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis

Melanie Fritsch, Saskia Diana Günther, Robin Schwarzer et al. · Nature · 2019 · 1.1K citations

Signal Transduction, Signaling Pathway, Apoptosis +11

<i>PTEN</i> Loss Contributes to Erlotinib Resistance in EGFR-Mutant Lung Cancer by Activation of Akt and EGFR

Martin L. Sos, Mirjam Koker, Barbara A. Weir et al. · Cancer Research · 2009 · 492 citations · Full text

Egfr-mutant Lung Cancer, Pten Loss, Cancer Biology +16

B-cell–specific conditional expression of Myd88p.L252P leads to the development of diffuse large B-cell lymphoma in mice

Gero Knittel, Paul Liedgens, Darya Korovkina et al. · Blood · 2016 · 109 citations · Full text

BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1β Maturation in Macrophages

Dhruv Chauhan, Eva Bartok, Moritz M. Gaidt et al. · Cell Reports · 2018 · 97 citations · Full text

Inflammation, Inflammatory Responses, Cytokine +14

Tumour-infiltrating neutrophils counteract anti-VEGF therapy in metastatic colorectal cancer

Lars M. Schiffmann, Melanie Fritsch, Florian Gebauer et al. · British Journal of Cancer · 2018 · 86 citations · Full text