Rita Perego

High-Throughput NMR-Based Screening with Competition Binding Experiments

Claudio Dalvit, Maria M. Flocco, Stefan Knapp et al. · Journal of the American Chemical Society · 2002 · 153 citations

Engineering, Hit Identification, Magnetic Resonance +16

Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a

Nikolaus Schiering, Stefan Knapp, M. Marconi et al. · Proceedings of the National Academy of Sciences · 2003 · 152 citations · Full text

Discovery of 2-[1-(4,4-Difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1<i>H</i>-isoindole-4-carboxamide (NMS-P118): A Potent, Orally Available, and Highly Selective PARP-1 Inhibitor for Cancer Therapy

Gianluca Papeo, Helena Posteri, Daniela Borghi et al. · Journal of Medicinal Chemistry · 2015 · 139 citations · Full text

Cancer Therapy, Drug Target, Pharmacotherapy +18

Identification of 4,5-Dihydro-1<i>H</i>-pyrazolo[4,3-<i>h</i>]quinazoline Derivatives as a New Class of Orally and Selective Polo-Like Kinase 1 Inhibitors

Italo Beria, Dario Ballinari, J. A. Bertrand et al. · Journal of Medicinal Chemistry · 2010 · 80 citations · Full text

Activation of Zap-70 Tyrosine Kinase Due to a Structural Rearrangement Induced by Tyrosine Phosphorylation and/or ITAM Binding

Carlo Visco, Giovanni Magistrelli, Roberta Bosotti et al. · Biochemistry · 2000 · 31 citations