Design, Synthesis, and Pharmacological Characterization of (+)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY354740):  A Potent, Selective, and Orally Active Group 2 Metabotropic Glutamate Receptor Agonist Possessing Anticonvulsant and Anxiolytic Properties

James A. Monn, Matthew J. Valli, Steven M. Massey, +12

Journal of Medicinal Chemistry

Pharmacological CharacterizationActive Group 2Psychotropic MedicationPharmacotherapyChemical Biology +14

Thallium in organic synthesis. XXIII. Electrophilic aromatic thallation. Kinetics and applications to orientation control in the synthesis of aromatic iodides

Edward C. Taylor, Frank Kienzle, Roger L. Robey, +2

Journal of the American Chemical Society

Organic Material ChemistryChemical EngineeringNovel OrganocatalystsEngineeringAltmetric Attention Score +7

Application of metalated enamines to alkaloid synthesis. An expedient approach to the synthesis of morphine-based analgesics

David A. Evans, Charles H. Mitch, Ralph Thomas, +2

Journal of the American Chemical Society

Pain MedicineAltmetric Attention ScoreOrganic ChemistryPharmacotherapyChemistry +15

A Peroxisome Proliferator-Activated Receptor α/γ Dual Agonist with a Unique in Vitro Profile and Potent Glucose and Lipid Effects in Rodent Models of Type 2 Diabetes and Dyslipidemia

Anne Reifel‐Miller, Keith A. Otto, Eric D. Hawkins, +18

Molecular Endocrinology

Insulin SignalingMetabolic SyndromeMetabolic SignalingDual AgonistHealth Sciences +15

Thallium in organic synthesis. XXXIV. Oxidations of acetylenes with thallium(III) nitrate (TTN)

Alexander McKillop, O. H. OLDENZIEL, Brian P. Swann, +2

Journal of the American Chemical Society

Chemical EngineeringEngineeringHeterocyclicAltmetric Attention ScoreOrganic Chemistry +5

Thallium in organic synthesis. 43. Novel oxidative rearrangements with thallium(III) nitrate (TTN) in trimethyl orthoformate (TMOF)

Edward C. Taylor, Roger L. Robey, Kecen Liu, +6

Journal of the American Chemical Society

Chemical EngineeringEngineeringTrimethyl OrthoformateHeterocyclicAltmetric Attention Score +9

2-Alkoxydihydrocinnamates as PPAR agonists. Activity modulation by the incorporation of phenoxy substituents

José A. Martín, Dawn A. Brooks, Lourdes Prieto, +24

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyActivity ModulationPharmacological StudyBiochemistryMedicine +8

Synthesis of [11C]dapoxetine · HCl, a serotonin re-uptake inhibitor: Biodistribution in rat and preliminary PET imaging in the monkey

Eli Livni, W. Satterlee, Roger L. Robey, +7

Nuclear Medicine and Biology

Positron Emission TomographyPharmacological StudySerotonin Re-uptake InhibitorMedicinePreliminary Pet Imaging +7

Thallium in organic synthesis. XIV. Orientation control in an electrophilic aromatic substitution reaction

Edward C. Taylor, Frank Kienzle, Roger L. Robey, +1

Journal of the American Chemical Society

EngineeringHeterocyclicChemical TransformationOrganic ChemistrySocial Media Presence +8

A Facile Synthesis of 2‐Alkynoic Esters

Edward C. Taylor, Roger L. Robey, Alexander McKillop

Angewandte Chemie International Edition in English

Organic ChemistryFacile SynthesisSynthetic ChemistryChemistry