DJ‐1 has a role in antioxidative stress to prevent cell death

Takahiro Taira, Yoshiro Saito, Takeshi Niki, +3

EMBO Reports

Redox SignalingAntioxidative StressApoptosisImmunologyCell Death +6

DJ-1 Positively Regulates the Androgen Receptor by Impairing the Binding of PIASxα to the Receptor

Kazuko Takahashi, Takahiro Taira, Takeshi Niki, +3

Journal of Biological Chemistry

The Crystal Structure of DJ-1, a Protein Related to Male Fertility and Parkinson's Disease

Kazuya Honbou, Nobuo Suzuki, Masataka Horiuchi, +4

Journal of Biological Chemistry

DJBP: a novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex.

Takeshi Niki, Kazuko Takahashi-Niki, Takahiro Taira, +2

PubMed

Androgen ReceptorGeneticsMolecular BiologyEpigeneticsDjbp-hdac Complex +16

Association of DJ-1 with chaperones and enhanced association and colocalization with mitochondrial Hsp70 by oxidative stress

Hong Mei Li, Takeshi Niki, Takahiro Taira, +2

Free Radical Research

Neurodegenerative DiseasesMitochondrial FunctionBiochemistryProtein FoldingMedicine +13

Reduced anti-oxidative stress activities of DJ-1 mutants found in Parkinson’s disease patients

Kazuko Takahashi-Niki, Takeshi Niki, Takahiro Taira, +2

Biochemical and Biophysical Research Communications

Neurodegenerative DiseasesBiochemistryDj-1 MutantsParkinson DiseaseAnti-oxidative Stress Activities +6

DJ-1 restores p53 transcription activity inhibited by Topors/p53BP3

Yumi Shinbo, Takahiro Taira, Takeshi Niki, +2

International Journal of Oncology

Reductive StressTranscriptional RegulationNeurodegenerative DiseasesCell RegulationMedicine +10

DJ-1, a Target Protein for an Endocrine Disrupter, Participates in the Fertilization in Mice.

Masahiko Okada, Kenichi Matsumoto, Takeshi Niki, +3

Biological and Pharmaceutical Bulletin

SpermatogenesisFertilityEndocrine DisrupterImmunologySemen Analysis +23

Human DJ-1-specific Transcriptional Activation of Tyrosine Hydroxylase Gene

Shizuma Ishikawa, Takahiro Taira, Kazuko Takahashi-Niki, +3

Journal of Biological Chemistry

Oxidative Status of DJ-1-dependent Activation of Dopamine Synthesis through Interaction of Tyrosine Hydroxylase and 4-Dihydroxy-l-phenylalanine (l-DOPA) Decarboxylase with DJ-1

Shizuma Ishikawa, Takahiro Taira, Takeshi Niki, +5

Journal of Biological Chemistry