Yoshitsugu Adachi

Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic

Youn‐Bok Lee, Han-Jou Chen, João Peres et al. · Cell Reports · 2013 · 483 citations · Full text

Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes

Danielle C. Diaper, Yoshitsugu Adachi, Ben Sutcliffe et al. · Human Molecular Genetics · 2013 · 159 citations · Full text

Genetics, Synaptic Transmission, Motor Control +16

A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration

Daniel A. Solomon, Alan Stepto, Wing Hei Au et al. · Brain · 2018 · 90 citations · Full text

Genetics, Dipeptide-repeat Protein, Synaptic Signaling +19

Drosophila TDP-43 dysfunction in glia and muscle cells cause cytological and behavioural phenotypes that characterize ALS and FTLD

Danielle C. Diaper, Yoshitsugu Adachi, Luke Lazarou et al. · Human Molecular Genetics · 2013 · 83 citations · Full text

Neurodegenerative Diseases, Muscle Cells, Developmental Biology +13

C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity

Youn‐Bok Lee, Pranetha Baskaran, Jorge Gomez-Deza et al. · Human Molecular Genetics · 2017 · 81 citations · Full text

Key Role, Genetics, Molecular Biology +18