Alan Stepto

Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes

Danielle C. Diaper, Yoshitsugu Adachi, Ben Sutcliffe et al. · Human Molecular Genetics · 2013 · 159 citations · Full text

Genetics, Synaptic Transmission, Motor Control +16

A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration

Daniel A. Solomon, Alan Stepto, Wing Hei Au et al. · Brain · 2018 · 90 citations · Full text

Genetics, Dipeptide-repeat Protein, Synaptic Signaling +19

C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity

Youn‐Bok Lee, Pranetha Baskaran, Jorge Gomez-Deza et al. · Human Molecular Genetics · 2017 · 81 citations · Full text

Key Role, Genetics, Molecular Biology +18

A lineage-related reciprocal inhibition circuitry for sensory-motor action selection

Benjamin Kottler, Vincenzo G. Fiore, Zoe N. Ludlow et al. · 2017 · 13 citations · Full text

Brain Mechanism, Circuit Neuroscience, Motor Control +20