A. Bom - Concepedia

Author

A. Bom

Erasmus University Rotterdam

Also Known As

A BOM, A Bom, A H Bom, A. Bom, A. H. A. Bom, A. H. Bom, A.H. Bom, Anne- Sophie Bom, Anton Bom, Anton H Bom

Publications

2.1K

Citations

H-Index

Concepts

All Affiliations

Erasmus University Rotterdam Radboud University Medical Center Radboud University Nijmegen Springhouse Office of the Chief Scientist

About

A. Bom is an author at Erasmus University Rotterdam specializing in medicine, pharmacology, and pharmacotherapy.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	13	19	856
2	Health Sciences	5	5	274
3	Social Sciences	3	3	43
4	Natural Sciences	2	2	36
5	Humanities	1	1	14

A. Bom

Publications

1.9K

Citations

H-Index

Page 1

	Year	Citations
A Novel Concept of Reversing Neuromuscular Block: Chemical Encapsulation of Rocuronium Bromide by a Cyclodextrin-Based Synthetic Host The discovery of Org 25969 is the result of teamwork with contributions from a number of scientists both inside Organon and outside the company. We would like in particular to acknowledge the following scientists for their invaluable contributions: E. Hutchinson, D. Stevenson, R. Roy, and J. Pick for scaling-up the synthesis; F. Hope, S. Miller, and R. Mason for various in vitro and in vivo pharmacological testing; R. Watson, B. Montgomery, P. Desmond, and A. Osprey for all their analytical effort; and R. McGuire and J. Mestres for graphical presentation of the X-ray crystal structure of the Org 25969–rocuronium complex (Figure 3). We would also like to thank Prof. A. Cooper of Glasgow University who has critically reproduced our calorimetry data of Org 25969–rocuronium complexation (Figure 2). A. Bom, Mark Philip Bradley, Ken Cameron, Angewandte Chemie International Edition	2002	451
Cyclodextrin-Derived Host Molecules as Reversal Agents for the Neuromuscular Blocker Rocuronium Bromide: Synthesis and Structure−Activity Relationships Julia M. Adam, David Jonathan Bennett, A. Bom, Journal of Medicinal Chemistry	2002	230
A Novel Concept of Reversing Neuromuscular Block: Chemical Encapsulation of Rocuronium Bromide by a Cyclodextrin-Based Synthetic Host A. Bom, Mark Philip Bradley, Ken Cameron, Angewandte Chemie Neuromodulation TherapiesPharmacotherapyBiomedical EngineeringChemical EncapsulationNeuromuscular Blockade	2002	226
Sugammadex, a new reversal agent for neuromuscular block induced by rocuronium in the anaesthetized Rhesus monkey Hans D. de Boer, J. van Egmond, F. van de Pol, British Journal of Anaesthesia AnesthesiaAnaesthetized Rhesus MonkeyMedicineNeuromuscular BlockadeNew Reversal Agent	2006	152
Reversal of Neuromusclar Blockade and Simultaneous Increase in Plasma Rocuronium Concentration after the Intravenous Infusion of the Novel Reversal Agent Org 25970 Ola Epemolu, A. Bom, F. Hope, Anesthesiology	2003	149
Preclinical pharmacology of sugammadex A. Bom, F. Hope, Samantha Rutherford, Journal of Critical Care Molecular PharmacologyPharmaceutical ScienceMedicineClinical PharmacologyPharmacotherapy	2009	127
Regional wall motion from radiopaque markers after intravenous and intracoronary injections of nifedipine. Patrick W. Serruys, Ronald W. Brower, Harald J. ten Katen, Circulation	1981	97
Reversal of Profound Rocuronium Neuromuscular Blockade by Sugammadex in Anesthetized Rhesus Monkeys Hans D. de Boer, J. van Egmond, F. van de Pol, Anesthesiology	2006	63
Chemical encapsulation of rocuronium by synthetic cyclodextrin derivatives: reversal of neuromuscular block in anaesthetized Rhesus monkeys Hans D. de Boer, J. van Egmond, F. van de Pol, British Journal of Anaesthesia MedicineCyclodextrin ProductionAnaesthetized Rhesus MonkeysNeuropharmacologyNeuroscience	2005	60
5‐Hydroxytryptamine‐induced tachycardia in the pig: possible involvement of a new type of 5‐hydroxytryptamine receptor A. Bom, Dirk J. Duncker, P.R. Saxena, British Journal of Pharmacology Porcine Heart RateRight AtriumNew TypeCardiovascular PharmacologyPharmacotherapy	1988	55

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