Concepedia

Dorothy J. Donnelly

DJ

8

Publications

441

Citations

8

H-Index

1965

Active since

Affiliations

Cancer Research UK Manchester Institute(Current)

Trinity College Dublin

Cancer Research UK

University of Manchester

Dorothy J. Donnelly is an author at Cancer Research UK Manchester Institute specializing in medicine, medicinal chemistry, and drug discovery.

Top concepts

Publications per year

1965–2023

8

Publications

8

Lomeguatrib, a Potent Inhibitor of <i>O</i>6-Alkylguanine-DNA-Alkyltransferase: Phase I Safety, Pharmacodynamic, and Pharmacokinetic Trial and Evaluation in Combination with Temozolomide in Patients with Advanced Solid Tumors

Malcolm Ranson, Mark R. Middleton, John Bridgewater et al. · Clinical Cancer Research · 2006 · 142 citations · Full text

O6-(4-bromothenyl)guanine improves the therapeutic index of temozolomide against A375M melanoma xenografts

Mark R. Middleton, Jane Kelly, Nicholas Thatcher et al. · International Journal of Cancer · 2000 · 77 citations

, , +18

Inactivation of <i>O</i><sup>6</sup>-Alkylguanine-DNA Alkyltransferase. 1. Novel <i>O</i><sup>6</sup>-(Hetarylmethyl)guanines Having Basic Rings in the Side Chain

R. Stanley McElhinney, Dorothy J. Donnelly, Joan E. McCormick et al. · Journal of Medicinal Chemistry · 1998 · 68 citations · Full text

, , +18

O6-(4-bromothenyl)guanine improves the therapeutic index of temozolomide against A375M melanoma xenografts

Mark R. Middleton, Jane Kelly, Nicholas Thatcher et al. · International Journal of Cancer · 2000 · 53 citations · Full text

, , +18

Effect of <i>O</i><sup>6</sup>‐(4‐bromothenyl)guanine on different temozolomide schedules in a human melanoma xenograft model

Mark R. Middleton, Nicholas Thatcher, T. Brian H. McMurry et al. · International Journal of Cancer · 2002 · 42 citations

, , +13

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