T. Brian H. McMurry

Lomeguatrib, a Potent Inhibitor of <i>O</i>6-Alkylguanine-DNA-Alkyltransferase: Phase I Safety, Pharmacodynamic, and Pharmacokinetic Trial and Evaluation in Combination with Temozolomide in Patients with Advanced Solid Tumors

Malcolm Ranson, Mark R. Middleton, John Bridgewater et al. · Clinical Cancer Research · 2006 · 142 citations · Full text

O6-(4-bromothenyl)guanine improves the therapeutic index of temozolomide against A375M melanoma xenografts

Mark R. Middleton, Jane Kelly, Nicholas Thatcher et al. · International Journal of Cancer · 2000 · 77 citations

Chemoprevention Strategy, Tumour Growth, A375m Melanoma Xenografts +18

Inactivation of <i>O</i>⁶-Alkylguanine-DNA Alkyltransferase. 1. Novel <i>O</i>⁶-(Hetarylmethyl)guanines Having Basic Rings in the Side Chain

R. Stanley McElhinney, Dorothy J. Donnelly, Joan E. McCormick et al. · Journal of Medicinal Chemistry · 1998 · 68 citations · Full text

Bioorganic Chemistry, Genetics, Molecular Biology +18

O6-(4-bromothenyl)guanine reverses temozolomide resistance in human breast tumour MCF-7 cells and xenografts

Mark Clemons, Jane Kelly, A J Watson et al. · British Journal of Cancer · 2005 · 59 citations · Full text

O6-(4-bromothenyl)guanine improves the therapeutic index of temozolomide against A375M melanoma xenografts

Mark R. Middleton, Jane Kelly, Nicholas Thatcher et al. · International Journal of Cancer · 2000 · 53 citations · Full text

Tumour Growth, A375m Melanoma Xenografts, Dermatology +18