R. Stanley McElhinney

Author

Also Known As

McElhinney, R.S., McElhinney, RS, R S McElhinney, R. McElhinney, R. S. MCELHINNEY, R. S. McELHINNEY, R. S. McElhinney, R. STANLEY McELHINNEY, R. Stanley McElhinney, R.S. McElhinney

Publications

867

Citations

H-Index

Concepts

All Affiliations

Trinity College Dublin Cancer Research UK Manchester Institute Cancer Research UK University of Manchester

About

R. Stanley McElhinney is an author at Trinity College Dublin specializing in natural sciences, medicine, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Natural Sciences	9	9	234
2	Medicine	8	8	345
3	Biochemistry	5	5	120
4	Engineering	4	4	57
5	Biomolecular Engineering	4	4	52

R. Stanley McElhinney

Publications

711

Citations

H-Index

Page 1

	Year	Citations
Lomeguatrib, a Potent Inhibitor of <i>O</i>6-Alkylguanine-DNA-Alkyltransferase: Phase I Safety, Pharmacodynamic, and Pharmacokinetic Trial and Evaluation in Combination with Temozolomide in Patients with Advanced Solid Tumors Malcolm Ranson, Mark R. Middleton, John Bridgewater, Clinical Cancer Research	2006	142
O6-(4-bromothenyl)guanine improves the therapeutic index of temozolomide against A375M melanoma xenografts Mark R. Middleton, Jane Kelly, Nicholas Thatcher, International Journal of Cancer Chemoprevention StrategyTumour GrowthA375m Melanoma XenograftsDermatologyTumor Biology	2000	77
Inactivation of <i>O</i><sup>6</sup>-Alkylguanine-DNA Alkyltransferase. 1. Novel <i>O</i><sup>6</sup>-(Hetarylmethyl)guanines Having Basic Rings in the Side Chain R. Stanley McElhinney, Dorothy J. Donnelly, Joan E. McCormick, Journal of Medicinal Chemistry Bioorganic ChemistryGeneticsMolecular BiologyMolecular GeneticsHeterocycle Chemistry	1998	68
O6-(4-bromothenyl)guanine reverses temozolomide resistance in human breast tumour MCF-7 cells and xenografts Mark Clemons, Jane Kelly, A J Watson, British Journal of Cancer	2005	59
Synthesis of Potential Anticancer Agents. V. Azetidines<sup>1,2</sup> Wyman R. Vaughan, ROBERT S. KLONOWSKI, R. Stanley McElhinney, The Journal of Organic Chemistry Molecular PharmacologyMedicinal ChemistryPharmaceutical SciencePharmaceutical ResearchTherapeutic Drug Monitoring	1961	55
O6-(4-bromothenyl)guanine improves the therapeutic index of temozolomide against A375M melanoma xenografts Mark R. Middleton, Jane Kelly, Nicholas Thatcher, International Journal of Cancer Tumour GrowthA375m Melanoma XenograftsDermatologyTumor BiologyMedicinal Chemistry	2000	53
Effect of <i>O</i><sup>6</sup>‐(4‐bromothenyl)guanine on different temozolomide schedules in a human melanoma xenograft model Mark R. Middleton, Nicholas Thatcher, T. Brian H. McMurry, International Journal of Cancer Daily TemozolomideOncologyMedicinePhotocarcinogenesisMelanoma	2002	42
Sensitization of a human ovarian cancer cell line to temozolomide by simultaneous attenuation of the Bcl-2 antiapoptotic protein and DNA repair by <i>O</i>6-alkylguanine-DNA alkyltransferase Vincent A. Barvaux, Paul Lorigan, Malcolm Ranson, Molecular Cancer Therapeutics	2004	38
Dual repair modulation reverses Temozolomide resistance <i>in vitro</i> Vincent A. Barvaux, Malcolm Ranson, Robert Brown, Molecular Cancer Therapeutics Molecular BiologyTherapeuticsMgmt Pseudosubstrate OEpigeneticsDrug Resistance	2004	30
QSAR and Chemical Read-Across Analysis of 370 Potential MGMT Inactivators to Identify the Structural Features Influencing Inactivation Potency Guohui Sun, Peiying Bai, Tengjiao Fan, Pharmaceutics	2023	26

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