Effects of thromboxane synthetase inhibitors on aggregation of rabbit platelets

Jun Naito, Hidetada Komatsu, Arao Ujiie, +3

European Journal of Pharmacology

ThrombopoiesisThrombosisPlatelet Aggregation InhibitorsCardiovascular DiseaseBlood Platelet +10

Reductions in Bone Mass, Structure, and Strength in Axial and Appendicular Skeletons Associated With Increased Turnover After Ovariectomy in Mature Cynomolgus Monkeys and Preventive Effects of Clodronate

Fumiaki Itoh, Masami Kojima, Hanako Furihata-Komatsu, +4

Journal of Bone and Mineral Research

NutritionNormal Calcium DietAppendicular Skeletons AssociatedOsteoporosisOrthopaedic Surgery +16

Mechanism f inhibitory action of tranilast on the release of slow reacting substance of anaphylaxis (SRS-A) in vitro: Effect of tranilast on the release of arachidonic acid and its metabolites.

Hidetada Komatsu, Masami Kojima, Naoyuki Tsutsumi, +5

The Japanese Journal of Pharmacology

Effect of a thromboxane A2 synthetase inhibitor (OKY-046 · HCl) on airway hyperresponsiveness in guinea pigs

Hidetada Komatsu, Yasuo Takehana, Shinji Kikuchi, +5

European Journal of Pharmacology

Molecular PharmacologyGuinea PigsLung InflammationMedicinePhysiology +8

Effect of tranilast, an anti-allergic drug, on the human keloid tissues.

Haruo SUZAWA, Shinji Kikuchi, Kiyoshi Ichikawa, +8

Folia Pharmacologica Japonica

Study of the Mechanism of Inhibitory Action of Tranilast on Chemical Mediator Release

Hidetada Komatsu, Masami Kojima, Naoyuki Tsutsumi, +5

The Japanese Journal of Pharmacology

Mast Cell DisorderImmunologyAntigen-induced Histamine ReleasePlatelet AggregationCellular Physiology +14

Effect of tranilast, an anti-allergic drug, on carrageenin-induced granulation and capillary permeability in rats.

Haruo SUZAWA, Kiyoshi Ichikawa, Shinji Kikuchi, +4

Folia Pharmacologica Japonica

DermatologyCarrageenin-induced GranulationCellular PhysiologyOxidative StressInflammation +16

Effects of dopamine d2 receptor agonists in a pituitary transplantation‐induced hyperprolactinaemia/anovulation model in rats

Makoto Moro, Yoichi Inada, Hiroshi Miyata, +3

Clinical and Experimental Pharmacology and Physiology

Animal PhysiologyKidney CapsuleTransplantationXenotransplantationPituitary Gland +12

Inhibitory action of OKY-046HCl, a specific TXA2 synthetase inhibitor, on platelet activating factor(PAF)-induced airway hyperresponsiveness of guinea pigs: Role of TXA2 in development of PAF-induced nonspecific airway hyperresponsiveness.

Yasuo Takehana, Shuichiro Hamano, Shinji Kikuchi, +3

The Japanese Journal of Pharmacology

Beneficial Effect of OKY-046, a Selective Thromboxane A2 Synthetase Inhibitor, on Experimental Cerebral Vasospasm

Hidetada Komatsu, Yasuo Takehana, Shuichiro Hamano, +2

The Japanese Journal of Pharmacology