Yasuo Takehana

Tranilast inhibits the proliferation, chemotaxis and tube formation of human microvascular endothelial cells <i>in vitro</i> and angiogenesis <i>in vivo</i>

Masayuki Isaji, Hiroshi Miyata, Yoshiyuki Ajisawa et al. · British Journal of Pharmacology · 1997 · 100 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +14

Suppression of laser-induced choroidal neovascularization by oral tranilast in the rat.

Yasuo Takehana, Tomohiro Kurokawa, T. Kitamura et al. · PubMed · 1999 · 70 citations

Medicine, Ophthalmology, Surgery +15

Effect of a thromboxane A2 synthetase inhibitor (OKY-046 · HCl) on airway hyperresponsiveness in guinea pigs

Hidetada Komatsu, Yasuo Takehana, Shinji Kikuchi et al. · European Journal of Pharmacology · 1990 · 24 citations

Medicine, Pharmacology, Pharmacodynamics +7

Crosstalk between tumor necrosis factor-alpha signaling and aryl hydrocarbon receptor signaling in nuclear factor –kappa B activation: A possible molecular mechanism underlying the reduced efficacy of TNF-inhibitors in rheumatoid arthritis by smoking

Takuro Nii, Kentaro Kuzuya, Daijiro Kabata et al. · Journal of Autoimmunity · 2018 · 22 citations

Life Sciences, Immunology, Pharmacology +16

Inhibitory action of OKY-046HCl, a specific TXA2 synthetase inhibitor, on platelet activating factor(PAF)-induced airway hyperresponsiveness of guinea pigs: Role of TXA2 in development of PAF-induced nonspecific airway hyperresponsiveness.

Yasuo Takehana, Shuichiro Hamano, Shinji Kikuchi et al. · The Japanese Journal of Pharmacology · 1990 · 13 citations · Full text

Life Sciences, Pharmacology, Cell Signaling +6