Shi-Quan Hu

Mapping the Functional Surface of Insulin by Design: Structure and Function of a Novel A-Chain Analogue

Qing‐Xin Hua, Shi-Quan Hu, Bruce H. Frank et al. · Journal of Molecular Biology · 1996 · 109 citations

Biochemistry, Functional Surface, Protein Folding +9

Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonists

Brian J. Smith, Kun Huang, G.K.-W. Kong et al. · Proceedings of the National Academy of Sciences · 2010 · 107 citations · Full text

How Insulin Binds: the B-Chain α-Helix Contacts the L1 β-Helix of the Insulin Receptor

Kun Huang, Bin Xu, Shi-Quan Hu et al. · Journal of Molecular Biology · 2004 · 74 citations

Signal Transduction, Molecular Physiology, Biochemistry +9

Hierarchical Protein Folding:  Asymmetric Unfolding of an Insulin Analogue Lacking the A7−B7 Interchain Disulfide Bridge

Qing‐Xin Hua, Satoe H. Nakagawa, Wenhua Jia et al. · Biochemistry · 2001 · 70 citations

Design of an Active Ultrastable Single-chain Insulin Analog

Qing‐xin Hua, Satoe H. Nakagawa, Wenhua Jia et al. · Journal of Biological Chemistry · 2008 · 67 citations · Full text

Insulin Replacement Therapy, Engineering, Protein Assembly +19