L. Ruel

Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of β-catenin,a component of the presenilin protein complex

Masaki Nishimura, Gang Yu, Georges Lévesque et al. · Nature Medicine · 1999 · 222 citations

Neurodegenerative Diseases, Alzheimer's Disease, Presenilin Mutations +9

An early embryonic product of the gene shaggy encodes a serine/threonine protein kinase related to the CDC28/cdc2+ subfamily.

Marc Bourouis, Paul H. Moore, L. Ruel et al. · The EMBO Journal · 1990 · 154 citations · Full text

Signal Transduction, Developmental Biology, Signaling Pathway +8

Functional significance of a family of protein kinases encoded at the shaggy locus in Drosophila.

L. Ruel, Véronique Pantesco, Yves Lutz et al. · The EMBO Journal · 1993 · 69 citations · Full text

Developmental Biology, Shaggy Locus, Genetics +7

Dynamic phosphorylation of the kinesin Costal-2 in vivo reveals requirement of fused kinase activity for all levels of hedgehog signalling

Sophie Raisin, L. Ruel, Nadia Ranieri et al. · Developmental Biology · 2010 · 17 citations

Developmental Biology, Signal Transduction, Signaling Pathway +10

Cholesterol modification is necessary for controlled planar long-range activity of Hedgehog in Drosophila epithelia

Armel Gallet, L. Ruel, Laurence Staccini-Lavenant et al. · HAL (Le Centre pour la Communication Scientifique Directe) · 2006 · 15 citations