Marjon Al

Inactivating PSMB5 Mutations and P-Glycoprotein (Multidrug Resistance-Associated Protein/ATP-Binding Cassette B1) Mediate Resistance to Proteasome Inhibitors: Ex Vivo Efficacy of (Immuno)Proteasome Inhibitors in Mononuclear Blood Cells from Patients with Rheumatoid Arthritis

Sue Ellen Verbrugge, Yehuda G. Assaraf, Ben A. C. Dijkmans et al. · Journal of Pharmacology and Experimental Therapeutics · 2012 · 107 citations

Medicine, Pharmacology, Pharmacotherapy +11

IgA Complexes in Plasma and Synovial Fluid of Patients with Rheumatoid Arthritis Induce Neutrophil Extracellular Traps via FcαRI

Esil Aleyd, Marjon Al, Cornelis W. Tuk et al. · The Journal of Immunology · 2016 · 106 citations · Full text

Life Sciences, Immunology, Pathology +16

Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR

Sue Ellen Verbrugge, Marjon Al, Yehuda G. Assaraf et al. · Oncotarget · 2015 · 31 citations · Full text

Medicine, Oncology, Pharmacology +14

Overcoming bortezomib resistance in human B cells by anti-CD20/rituximab-mediated complement-dependent cytotoxicity and epoxyketone-based irreversible proteasome inhibitors

Sue Ellen Verbrugge, Marjon Al, Yehuda G. Assaraf et al. · Experimental Hematology and Oncology · 2013 · 19 citations · Full text

Life Sciences, Hematology, Pharmacology +17

Targeting histone methylation to reprogram the transcriptional state that drives survival of drug-tolerant myeloid leukemia persisters

Noortje van Gils, Han Verhagen, Michaël Broux et al. · iScience · 2022 · 12 citations · Full text

Life Sciences, Molecular Biology, Oncology +17